ID K0R9M3_THAOC Unreviewed; 1829 AA.
AC K0R9M3;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=HMG box domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=THAOC_35763 {ECO:0000313|EMBL:EJK45616.1};
OS Thalassiosira oceanica (Marine diatom).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC Coscinodiscophyceae; Thalassiosirophycidae; Thalassiosirales;
OC Thalassiosiraceae; Thalassiosira.
OX NCBI_TaxID=159749 {ECO:0000313|EMBL:EJK45616.1, ECO:0000313|Proteomes:UP000266841};
RN [1] {ECO:0000313|EMBL:EJK45616.1, ECO:0000313|Proteomes:UP000266841}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1005 {ECO:0000313|EMBL:EJK45616.1,
RC ECO:0000313|Proteomes:UP000266841};
RX PubMed=22835381; DOI=10.1186/gb-2012-13-7-r66;
RA Lommer M., Specht M., Roy A.S., Kraemer L., Andreson R., Gutowska M.A.,
RA Wolf J., Bergner S.V., Schilhabel M.B., Klostermeier U.C., Beiko R.G.,
RA Rosenstiel P., Hippler M., Laroche J.;
RT "Genome and low-iron response of an oceanic diatom adapted to chronic iron
RT limitation.";
RL Genome Biol. 13:R66-R66(2012).
CC -!- SIMILARITY: Belongs to the SBNO family.
CC {ECO:0000256|ARBA:ARBA00006992}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJK45616.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AGNL01048385; EJK45616.1; -; Genomic_DNA.
DR EnsemblProtists; EJK45616; EJK45616; THAOC_35763.
DR eggNOG; KOG0381; Eukaryota.
DR eggNOG; KOG1513; Eukaryota.
DR Proteomes; UP000266841; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0048583; P:regulation of response to stimulus; IEA:UniProt.
DR Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR026937; SBNO_Helicase_C_dom.
DR InterPro; IPR026741; SNO.
DR InterPro; IPR039187; SNO_AAA.
DR PANTHER; PTHR12706:SF30; PROTEIN STRAWBERRY NOTCH; 1.
DR PANTHER; PTHR12706; STRAWBERRY NOTCH-RELATED; 1.
DR Pfam; PF13872; AAA_34; 1.
DR Pfam; PF13871; Helicase_C_4; 2.
DR Pfam; PF00505; HMG_box; 1.
DR SMART; SM00398; HMG; 1.
DR SUPFAM; SSF47095; HMG-box; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50118; HMG_BOX_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00267};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00267};
KW Reference proteome {ECO:0000313|Proteomes:UP000266841}.
FT DOMAIN 80..148
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DOMAIN 967..1137
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DNA_BIND 80..148
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 1..78
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 136..227
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 754..914
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1577..1616
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1794..1829
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..33
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..69
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 148..179
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 193..210
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 211..226
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 791..829
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 870..887
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1577..1604
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1814..1829
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1829 AA; 203588 MW; 9B3619658E1A8455 CRC64;
MADLADLREG ENAPRSDFVV IDSFGEDENR DNRQNNPAAQ LQPLKAEAAG EKCRLEKTRN
DRDVGPENLE PLSHAHPSAP KQYMSAFFLY SEAKRDSIKQ ANPSASPQEI AKLLSRDFKA
MASEERAYWD KKAAEDKERY KREMENYDPT LTTATSSSDT GITSGASARK VSMSPPTYSQ
HKRPKKKKRN KKENKVKTEE AQTEAASDAE KEAEGEGEDV EEADEITYEP YQPAKLKYGR
PHPDPVVENA TLAAVAPPDV TYNLALPADI ISQGKLSGLQ LEAIVYGCQR HEMDLPVKKK
EVWQVEQGVV DEVPLRAGFL LGDGAGMGKG RTLAGFVMEN ISRGRQKHVW ISVSADLYED
AKRDLRDLGL DDYAADHCHN LGKLPYGKLS KKYRKGVMFL TYHQLIAKKS RGKETRLDQL
LEWCGGEDFG GLIMAKTIEL DANGNPKTTG KGPKKKELSS KTAIAVLDLQ KRLPRARVVY
CSATSVSHPK NLGLGLWGPG TQHPSGFKQF LGGLKSLGTG ASEFAFQTLR VSLCAVDDCQ
PNLPFDCSGD SRNAFEVHRT LSYESCEFDL VDGIGSEDVT KVYNKASQLW GELHSQLGEQ
TRQMEANARV EENMKKCLDK GIPVTQDMRY HMDLIRDSDS EPDEDSADEE ERKFRRKCRR
RAPKQLQSLF WSAHQRFFRS LCIATKVPKA IELAKESLEN DKCVVIGLQS TGEARAKGAT
KAAGFSNDQG ELDDFVSAPN EDLKRVIMMM FPLPPKPRGV NPPSFLNPNN RKTNDDDLSL
TEDDEGTEAE PEEVQNRSRS RRGRARKTVD YSEMGIDDDG YEVNGKAAGR KRKQSKKTSK
TSKKKEKRGS DDESDYADDE SSIDLSDPPS DDEAATKKGE PKGDAASDDD TFATAQDDED
SSDAEDYQPK NGKSWESKRL NWDEIELNVK KSDLTVETER RIAYRRAAAT VHKYLQSVDG
LDLPPNPLDE LLNKLGGPSM VAELTGRKIR QVQCINKETG QSFVRIEKRK GVKSFDKVNI
EEKEAFQSGE KNVAILSEAA STGISLQADH RVQNQRRRVH ITLELPWSAD KAIQQLGRTH
RANQSSGPEY KFLISDVGGE KRFAAAVAKR LALMGALTQG DRRSTGQSSS LGLGNFDMDN
KFGNKALRDM LGEVWKMNAR SLSEIENRHA SGALEIIDKH LSVVLDDTPA GADWRTSLAP
YDDDGETIHS YYSMMQSFLT SSRLIRFTEK RVEAIKNGKG LHQLMQSLED GDCSQEECLT
QLNEQVEESK SLGLNFNAVA RLFLYDVGVT QESSCASKSR PPINVAKFLN RCLGLPLSRQ
AMLTNHFLKW LEKEIKDAKR TGRYDIGIKT LSGNEVSIEK PRAFCFRGLD AKDDRVLLYS
VNIDRGMTSD TALDLWDEVK NNGNDSGSRI KTGFYYDDRT IFKQCDRMFL IINQGRTSTS
AIVARPNAGR GTFAVSADAC LIQTQGTSLA SLFAAVRLTP NFSSPVKNDY VLTHLLGGFA
ALKRCNDLTI VKQKWDQEFE LADLPSDEMY QRSCYGRQFS TVAFGGEVVP VLSKLLAAAN
PGGINNQDED RRTLPSIVRI EPEQHEKKKI TAAQSPRRSD DEDHDEADGE SPPAVGQNVA
CKLLGSNILR GEVVECKDDT TYTAVFTNGS SVELNLEEVS KARQLFSNEL EKLMNVNVSK
ADASNIGTKA SIAEKESAPR PLMADGDDIP DDCERAYEVE FQGDTPKLLV GLQFPKVKRI
WYNSTTQLHE EVDMWEVAPD STSVKKEIWV VTPAHAKPPS PLLYLTKGQY LRKPRKNTNK
TIHGAPRARQ IAPQPRDSIK RRLATLKED
//
