ID   K0RJV3_THAOC            Unreviewed;       754 AA.
AC   K0RJV3;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=CobW C-terminal domain-containing protein {ECO:0000259|SMART:SM00833};
GN   ORFNames=THAOC_28167 {ECO:0000313|EMBL:EJK52544.1};
OS   Thalassiosira oceanica (Marine diatom).
OC   Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC   Coscinodiscophyceae; Thalassiosirophycidae; Thalassiosirales;
OC   Thalassiosiraceae; Thalassiosira.
OX   NCBI_TaxID=159749 {ECO:0000313|EMBL:EJK52544.1, ECO:0000313|Proteomes:UP000266841};
RN   [1] {ECO:0000313|EMBL:EJK52544.1, ECO:0000313|Proteomes:UP000266841}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCMP1005 {ECO:0000313|EMBL:EJK52544.1,
RC   ECO:0000313|Proteomes:UP000266841};
RX   PubMed=22835381; DOI=10.1186/gb-2012-13-7-r66;
RA   Lommer M., Specht M., Roy A.S., Kraemer L., Andreson R., Gutowska M.A.,
RA   Wolf J., Bergner S.V., Schilhabel M.B., Klostermeier U.C., Beiko R.G.,
RA   Rosenstiel P., Hippler M., Laroche J.;
RT   "Genome and low-iron response of an oceanic diatom adapted to chronic iron
RT   limitation.";
RL   Genome Biol. 13:R66-R66(2012).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC         Evidence={ECO:0000256|ARBA:ARBA00001702};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC         Evidence={ECO:0000256|ARBA:ARBA00001702};
CC   -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC       subfamily. {ECO:0000256|ARBA:ARBA00034320}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EJK52544.1}.
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DR   EMBL; AGNL01039620; EJK52544.1; -; Genomic_DNA.
DR   AlphaFoldDB; K0RJV3; -.
DR   EnsemblProtists; EJK52544; EJK52544; THAOC_28167.
DR   eggNOG; KOG2743; Eukaryota.
DR   Proteomes; UP000266841; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd03112; CobW-like; 1.
DR   Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR036627; CobW-likC_sf.
DR   InterPro; IPR011629; CobW-like_C.
DR   InterPro; IPR003495; CobW/HypB/UreG_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR13748:SF62; COBW DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR13748; COBW-RELATED; 1.
DR   Pfam; PF02492; cobW; 1.
DR   Pfam; PF07683; CobW_C; 1.
DR   SMART; SM00833; CobW_C; 1.
DR   SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000266841}.
FT   DOMAIN          477..572
FT                   /note="CobW C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00833"
FT   REGION          1..96
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          135..161
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        36..51
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   754 AA;  83734 MW;  046E86ACFD8DE0A7 CRC64;
     MRHLRCGSVE RSGPVESSRP TGKADPVQEA TVEDGVQGRR GIRHEGGRDD CAGLAEAVGG
     NPGNPGEPYT PKQKQQLIDK PGRRATDRPS KSLNSVAAVS TEDTIANRAA TPPGPSPLPG
     GVAVRIRDIQ FPAARQRGGK VTGHSGKTAR DGIASTSERT NRRPTVHRWL FEVDGVRGHG
     PAQWTRRRAE GTRLSRIDPV VAPNTARVSE KVTQEKSSSA SSHQMTPTVW FFPKQLARSC
     LGRAYIPPSS WSSSRPCASY HRIPPTTSRR TTKGMRFAVI ENEFGEIGVD QRILNERVND
     EVIEGASQVT GPWDVRGDLV DALNRLYKKV DTFDGVIIET TGLADPAPVV QTFFAEVNSD
     STLEEKYKLD AIITVVDAKY IIQRLDETKG TEAEQQVCMA DKIILNKMDL VQNDGEADDI
     EDRLRSLNPT APIFRCSESK ISPKELLNVG SFDLEKVLEI DPFFLGEAKQ PKHDNAVSSI
     SAKYDGNVNR TLLEVWIRRL LKDYSGDQLY RYKGICSIQG QDERMVFQGV GHFFNSTYGA
     PWKDGEKRES TFVFIGRNLD TDTLRDGFEA CREGAPLRFD VGTEVQVNIG QYVRARVLAH
     WDEGHAYRVH LLDEGTDVFA PVDIDQYIRE ANPVPRFPVG TRVECNMGPQ FVRGTVIAHW
     DSGNPYRVKL ESNGMDVCAP KDDDKFIRKA ENQGDLRFDV GTRVEANMGQ EYLPGTVIAQ
     WDMGNAYRVR LDGIGSNDIW APVDDDKWVR LLST
//