ID K0RTM1_THAOC Unreviewed; 710 AA.
AC K0RTM1;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE RecName: Full=PDZ domain-containing protein {ECO:0000259|SMART:SM00228};
GN ORFNames=THAOC_28538 {ECO:0000313|EMBL:EJK52216.1};
OS Thalassiosira oceanica (Marine diatom).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC Coscinodiscophyceae; Thalassiosirophycidae; Thalassiosirales;
OC Thalassiosiraceae; Thalassiosira.
OX NCBI_TaxID=159749 {ECO:0000313|EMBL:EJK52216.1, ECO:0000313|Proteomes:UP000266841};
RN [1] {ECO:0000313|EMBL:EJK52216.1, ECO:0000313|Proteomes:UP000266841}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1005 {ECO:0000313|EMBL:EJK52216.1,
RC ECO:0000313|Proteomes:UP000266841};
RX PubMed=22835381; DOI=10.1186/gb-2012-13-7-r66;
RA Lommer M., Specht M., Roy A.S., Kraemer L., Andreson R., Gutowska M.A.,
RA Wolf J., Bergner S.V., Schilhabel M.B., Klostermeier U.C., Beiko R.G.,
RA Rosenstiel P., Hippler M., Laroche J.;
RT "Genome and low-iron response of an oceanic diatom adapted to chronic iron
RT limitation.";
RL Genome Biol. 13:R66-R66(2012).
CC -!- SIMILARITY: Belongs to the peptidase S1C family.
CC {ECO:0000256|ARBA:ARBA00010541}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJK52216.1}.
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DR EMBL; AGNL01040234; EJK52216.1; -; Genomic_DNA.
DR AlphaFoldDB; K0RTM1; -.
DR EnsemblProtists; EJK52216; EJK52216; THAOC_28538.
DR eggNOG; KOG1320; Eukaryota.
DR Proteomes; UP000266841; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00987; PDZ_serine_protease; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.40.10.120; -; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR001940; Peptidase_S1C.
DR PANTHER; PTHR22939; SERINE PROTEASE FAMILY S1C HTRA-RELATED; 1.
DR PANTHER; PTHR22939:SF129; SERINE PROTEASE HTRA2, MITOCHONDRIAL; 1.
DR Pfam; PF13180; PDZ_2; 1.
DR Pfam; PF13365; Trypsin_2; 1.
DR PRINTS; PR00834; PROTEASES2C.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000266841}.
FT DOMAIN 591..681
FT /note="PDZ"
FT /evidence="ECO:0000259|SMART:SM00228"
FT REGION 292..334
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 295..311
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 318..334
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 710 AA; 76124 MW; 63D83784B1247400 CRC64;
MLQAVHSGGI CPSARCSTTA FVTTVARPSR SIRQSVVFAT PGGDVNAVSD EDGMGMDSGW
TTFGRVLLPS WASIKQKQEE GSSLDGGAML SNSTNDTSFD VTDEKSNAFD VAIGSLDDNN
STSIGSELGG DINETRVEDL ADGPDSMDSG NLTSPIEVAP RSLDKPSRIP RVISTVVKYI
QGRGRRVAKS AAIADEFQVV SEDTDEVVIS EHREDSKPIL SSFESSDIDK TTLSKKMKWA
RRRTRLHVLF NALRSAAFLF VLTLLAGNVL NQVVDLDDEG SFEVHYGKAL SSKAPKSLPK
SSPLEQDSPK KSPSPSSKKK LEPQATNVHT QPHNTYAVRG SQPLRLVASA VKRNGPAIVR
VETETDLDSK IAIDEEADDK GSRGDVFDGI PDVPSVPSQI DQVDFGQGSG IIIDSRGYCR
VLTNAHVVEG ADRIRIHLPD GRQFTAELAG SDPIVDVALL KIVPDPDGDS ELPVASIGNS
DSLECGQFVV AVGTPGGLDN SCTLGIVSGL KRSPKMVGIP DKLGALDYVQ TDAAINQGNS
GGALIDVESG NVIAINCCIR ANMEGTSFAI PINKALSIVD DLSEGRLVEH GYIGVHLMTM
NPSLARFHNR LSTGKRRIPE RSGVMVETIF KSSPAKDAGL KRYDYIESID GQRVRSADDA
HLLIDRAKPG KAIIIKIFRG QQEMDLKCSP KDLSKHLENL RKTKKAKGSS
//
