ID K0S224_THAOC Unreviewed; 650 AA.
AC K0S224;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Enoyl reductase (ER) domain-containing protein {ECO:0000259|SMART:SM00829};
GN ORFNames=THAOC_20989 {ECO:0000313|EMBL:EJK58854.1};
OS Thalassiosira oceanica (Marine diatom).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC Coscinodiscophyceae; Thalassiosirophycidae; Thalassiosirales;
OC Thalassiosiraceae; Thalassiosira.
OX NCBI_TaxID=159749 {ECO:0000313|EMBL:EJK58854.1, ECO:0000313|Proteomes:UP000266841};
RN [1] {ECO:0000313|EMBL:EJK58854.1, ECO:0000313|Proteomes:UP000266841}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1005 {ECO:0000313|EMBL:EJK58854.1,
RC ECO:0000313|Proteomes:UP000266841};
RX PubMed=22835381; DOI=10.1186/gb-2012-13-7-r66;
RA Lommer M., Specht M., Roy A.S., Kraemer L., Andreson R., Gutowska M.A.,
RA Wolf J., Bergner S.V., Schilhabel M.B., Klostermeier U.C., Beiko R.G.,
RA Rosenstiel P., Hippler M., Laroche J.;
RT "Genome and low-iron response of an oceanic diatom adapted to chronic iron
RT limitation.";
RL Genome Biol. 13:R66-R66(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJK58854.1}.
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DR EMBL; AGNL01024091; EJK58854.1; -; Genomic_DNA.
DR AlphaFoldDB; K0S224; -.
DR EnsemblProtists; EJK58854; EJK58854; THAOC_20989.
DR eggNOG; KOG1198; Eukaryota.
DR Proteomes; UP000266841; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd08273; MDR8; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR43189:SF1; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C1198.01; 1.
DR PANTHER; PTHR43189; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C1198.01-RELATED; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF13602; ADH_zinc_N_2; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000266841}.
FT DOMAIN 312..648
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
FT REGION 26..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 94..231
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 257..297
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 36..52
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 94..114
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 148..168
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 169..184
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 257..273
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 274..297
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 650 AA; 70185 MW; B0B8C23CB490C3B5 CRC64;
MVGFRKINKI NSVKVKGFTS RLSAFGVKKG AKTDQSKASA DTPDTSPEVT PEQQAEPLPG
PESAAAGPTA GGTEADEVLS GILKDLSIDP DIAIQQNKTD DVSEYSGGSA KSVDSETSEE
GEKEISIGEK VNMVIAAAEE IRMKKSSSPP QVGGTPLATA SSVDTPATEA GDKTKETEPK
NTKKPKKRVS LRSKKSKSPT PSKEVETNSE TPQHLSAVKH AGETGEESGA RAEFSTDFEG
QDFQGQDDKA VETSIEDQTF EDEPTKEGSM TDDTTFSEDN TFASGPGSID IEPSSSNKGS
VMNKDIFIHE AGGPNNLVVR AMYYTPLPST PEEVIIKVEA STVSFRDCML RRGLGVEKVS
FPFTPGCEVV GTISHLGNRA KRMGYRIGDR VVAMNRSGGG NGYYAKFHMD CVSPIISNKI
EAADAVCLVD VYMTAYQALR CGKNDGTPLT EANILVTDGY SPVGQAAVQL ALLEGANVYV
TTSETGQEEH MRSLGAKCLP YSPNKWLHKI KGKMDLVIDN TCLDSYDSSW NALSATGTLV
VTGITSLYNF TDYGDVGFGC DAFGDFRDYQ ARWATMKAKY IMSQTKFNDV YESFKKDPKQ
YSQELKYLCF LVENGTLKPK IAERVSIEEI PDAQRYLETG KVNGTIVCLP
//
