ID K0SCI1_THAOC Unreviewed; 678 AA.
AC K0SCI1;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Choline/carnitine acyltransferase domain-containing protein {ECO:0000259|Pfam:PF00755};
GN ORFNames=THAOC_16292 {ECO:0000313|EMBL:EJK63075.1};
OS Thalassiosira oceanica (Marine diatom).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC Coscinodiscophyceae; Thalassiosirophycidae; Thalassiosirales;
OC Thalassiosiraceae; Thalassiosira.
OX NCBI_TaxID=159749 {ECO:0000313|EMBL:EJK63075.1, ECO:0000313|Proteomes:UP000266841};
RN [1] {ECO:0000313|EMBL:EJK63075.1, ECO:0000313|Proteomes:UP000266841}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1005 {ECO:0000313|EMBL:EJK63075.1,
RC ECO:0000313|Proteomes:UP000266841};
RX PubMed=22835381; DOI=10.1186/gb-2012-13-7-r66;
RA Lommer M., Specht M., Roy A.S., Kraemer L., Andreson R., Gutowska M.A.,
RA Wolf J., Bergner S.V., Schilhabel M.B., Klostermeier U.C., Beiko R.G.,
RA Rosenstiel P., Hippler M., Laroche J.;
RT "Genome and low-iron response of an oceanic diatom adapted to chronic iron
RT limitation.";
RL Genome Biol. 13:R66-R66(2012).
CC -!- SIMILARITY: Belongs to the carnitine/choline acetyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005232, ECO:0000256|RuleBase:RU003801}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJK63075.1}.
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DR EMBL; AGNL01018456; EJK63075.1; -; Genomic_DNA.
DR AlphaFoldDB; K0SCI1; -.
DR EnsemblProtists; EJK63075; EJK63075; THAOC_16292.
DR eggNOG; KOG3717; Eukaryota.
DR OMA; MAMSSYE; -.
DR Proteomes; UP000266841; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.30.559.70; Choline/Carnitine o-acyltransferase, domain 2; 1.
DR InterPro; IPR000542; Carn_acyl_trans.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR039551; Cho/carn_acyl_trans.
DR InterPro; IPR042231; Cho/carn_acyl_trans_2.
DR PANTHER; PTHR22589:SF115; CARNITINE O-ACETYLTRANSFERASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR22589; CARNITINE O-ACYLTRANSFERASE; 1.
DR Pfam; PF00755; Carn_acyltransf; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR PROSITE; PS00440; ACYLTRANSF_C_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000256|RuleBase:RU003801};
KW Reference proteome {ECO:0000313|Proteomes:UP000266841};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003801}.
FT DOMAIN 65..658
FT /note="Choline/carnitine acyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00755"
FT ACT_SITE 377
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600542-1"
SQ SEQUENCE 678 AA; 75553 MW; E04C241309A4CD9A CRC64;
MLRRVISSQP RCRQSSKDII RTMSSTIKPW PQPMVESKGD YRAESFLEDH IGGKLYSQQR
TLPRLPIPEV KDTLDRFLPT ALPLAKSEEE KATLVKAVQQ FEGQSVELQK RLVERREGEM
KDSRFSYFFV SVFCSCQIQV RDPVVVNVSY FFHFSDDGSL PENASDKSLG VLRAASLLYS
SAKFRQLVAS GDLPFEAIGR KDPKTPLCST AYKYMFNACR VPRKVEDTYR IYDPALNSHA
IVACGGKFYS FDFVDGSGNP LPLPVIEQRL KKCVELSKSG PDMPMLGYLT SDDRDKCADA
REELLRLGGK SVEEALRVLE SGALLICLDE NESPVSKRQG SEIFWTGGLT SGHNRWFDKS
IQIICTENGK AGMNGEHSMM DGMPVVGFCD FITKKSYAEV SAESAERFSS TSAYESADEN
VKDIFARCAS DLAGVSGHVS GCKANFDELV SSHEMDVQSF QGYGSSGIKK MGYSPDAYVQ
MAMQLATYRL WGEQGGTYEA TQVRPFLHGR TETTRTVSPA SEAFIKQMGL RPKRDELDAD
KRGEKINLLR DAVSSHVKYI GSAAKAMGVD RHFLGLLLEV QDGESSPDLF SHPLYAVSKT
WRVSTSHLTH PRFDSWGYGE VTPDGVGLAY SIHPNHCMFC ISALKRHGWP ERLSALLEEA
LLEMQTLNDL EIAQKSKL
//
