ID K0SCZ4_THAOC Unreviewed; 1138 AA.
AC K0SCZ4;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Helicase ATP-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=THAOC_16571 {ECO:0000313|EMBL:EJK62804.1};
OS Thalassiosira oceanica (Marine diatom).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC Coscinodiscophyceae; Thalassiosirophycidae; Thalassiosirales;
OC Thalassiosiraceae; Thalassiosira.
OX NCBI_TaxID=159749 {ECO:0000313|EMBL:EJK62804.1, ECO:0000313|Proteomes:UP000266841};
RN [1] {ECO:0000313|EMBL:EJK62804.1, ECO:0000313|Proteomes:UP000266841}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1005 {ECO:0000313|EMBL:EJK62804.1,
RC ECO:0000313|Proteomes:UP000266841};
RX PubMed=22835381; DOI=10.1186/gb-2012-13-7-r66;
RA Lommer M., Specht M., Roy A.S., Kraemer L., Andreson R., Gutowska M.A.,
RA Wolf J., Bergner S.V., Schilhabel M.B., Klostermeier U.C., Beiko R.G.,
RA Rosenstiel P., Hippler M., Laroche J.;
RT "Genome and low-iron response of an oceanic diatom adapted to chronic iron
RT limitation.";
RL Genome Biol. 13:R66-R66(2012).
CC -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC {ECO:0000256|ARBA:ARBA00005446}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJK62804.1}.
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DR EMBL; AGNL01018610; EJK62804.1; -; Genomic_DNA.
DR AlphaFoldDB; K0SCZ4; -.
DR EnsemblProtists; EJK62804; EJK62804; THAOC_16571.
DR eggNOG; ENOG502SVQE; Eukaryota.
DR OMA; FRTHANN; -.
DR Proteomes; UP000266841; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000266841}.
FT DOMAIN 706..878
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 904..1069
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..28
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1138 AA; 126434 MW; 396B1EAA9A113E11 CRC64;
MERGLFRLPD WKDPQEQRLQ DRRQKRNPGI TDLSVQSPAS ELALGSVIAA SPQQMRNATN
PQYTPFRVCF ENHVKDQLLT CFDESSRQRA LEYTNTFIHL IGRSLQPPSQ LKEKLTEYAM
KLKDPLDLGE DGDAARILME ASKVWLLSGA ANMDVRALTA SIRGQLYTSG VIASTTANDD
EDLISGSTFV PTDNCANVAT EVELLFLFAF RMKYLGMQRH MDQVIQIRNS VSLSETSSLP
VDIAEHRRAT IERVVDTNII PGLLVSLMIE PCNRANGSNL IADFVAARAI LLRGSDCDEL
SLRSNNDISR HCNALLRALR HGVCSYLNTS SEEMECDDDF RTHANNLLSV ISASYSVDKI
CQLIRTALSI QRKSPSTVFK AFDPVTGRVF VDKYEVPKEI WGRLIPSALE KIRPAFYKLF
RCPELLDKLL NVKNAFVWDE ERSKVIVQNG ADREVVPLVS AVPSFDIEDA QKCIDICYSV
DRFSHAYLSF GACRASELDR MTFKQSQVIF NHLRFQIGSK KGRTHGRTQS SMEEHWMCPS
LSRYVVLLWL VVYPNIPAHL TKPRPDHASK VILPVFKELL NLDSKVGSKI ARDLIGQIHN
FIAPRPMSRI STTSPIARAM QHTASTHNSH YSSEIVEVNE DGAIIRPPMI IARDIHAALG
ECQFPLQSQR LDHVELDRSD FDSAARRCYQ NPTASVTNLQ FLLLQHICGK ETRSAVVHAG
CGTGKSGAYI LSLMSQEMYH IKKSKMIVIS PHNSLLSQHK MQASRYFSGT SLSVGSLLPS
DIAGISESRI PTDLTFVSIH AFKLLVSDHA QILENSGVTH CFIDEVHNLF QELFRHGSSW
CALRGLARMN WRIYCLSATV NSNISNCVGS YLGLRDSLDL IGSGTKYHVP NVAIRITNTT
DSAVITDVVN YVVSRVRSAG SGRKIHVITA TRDDAVSISN KLKESSISAM WLTSDATQQE
RLTIMQDWSE SSDPAVLSST FSDGIDCSLT EEVVVVRNGG SISRFIQAAG RVRPPKQVGA
GSVVRLFRTS YDPTTEGDIS SAVSFITAER MVPEGVSAES MFRQHFTLQG LNSILDGDTC
LRKSLLSAIG VQSVDCGMCE ACLSSNTLAR DTANAISVRE QHRLDEDYVL PEMPRSLS
//
