ID K0TBX2_THAOC Unreviewed; 531 AA.
AC K0TBX2;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Cullin family profile domain-containing protein {ECO:0000259|PROSITE:PS50069};
DE Flags: Fragment;
GN ORFNames=THAOC_03691 {ECO:0000313|EMBL:EJK74619.1};
OS Thalassiosira oceanica (Marine diatom).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC Coscinodiscophyceae; Thalassiosirophycidae; Thalassiosirales;
OC Thalassiosiraceae; Thalassiosira.
OX NCBI_TaxID=159749 {ECO:0000313|EMBL:EJK74619.1, ECO:0000313|Proteomes:UP000266841};
RN [1] {ECO:0000313|EMBL:EJK74619.1, ECO:0000313|Proteomes:UP000266841}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1005 {ECO:0000313|EMBL:EJK74619.1,
RC ECO:0000313|Proteomes:UP000266841};
RX PubMed=22835381; DOI=10.1186/gb-2012-13-7-r66;
RA Lommer M., Specht M., Roy A.S., Kraemer L., Andreson R., Gutowska M.A.,
RA Wolf J., Bergner S.V., Schilhabel M.B., Klostermeier U.C., Beiko R.G.,
RA Rosenstiel P., Hippler M., Laroche J.;
RT "Genome and low-iron response of an oceanic diatom adapted to chronic iron
RT limitation.";
RL Genome Biol. 13:R66-R66(2012).
CC -!- SIMILARITY: Belongs to the cullin family. {ECO:0000256|PROSITE-
CC ProRule:PRU00330, ECO:0000256|RuleBase:RU003829}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJK74619.1}.
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DR EMBL; AGNL01003493; EJK74619.1; -; Genomic_DNA.
DR AlphaFoldDB; K0TBX2; -.
DR EnsemblProtists; EJK74619; EJK74619; THAOC_03691.
DR eggNOG; KOG2166; Eukaryota.
DR Proteomes; UP000266841; Unassembled WGS sequence.
DR GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 1.20.1310.10; Cullin Repeats; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR045093; Cullin.
DR InterPro; IPR016157; Cullin_CS.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR001373; Cullin_N.
DR InterPro; IPR019559; Cullin_neddylation_domain.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11932; CULLIN; 1.
DR PANTHER; PTHR11932:SF123; CULLIN-4; 1.
DR Pfam; PF00888; Cullin; 1.
DR Pfam; PF10557; Cullin_Nedd8; 1.
DR SMART; SM00182; CULLIN; 1.
DR SMART; SM00884; Cullin_Nedd8; 1.
DR SUPFAM; SSF75632; Cullin homology domain; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS01256; CULLIN_1; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000266841}.
FT DOMAIN 74..184
FT /note="Cullin family profile"
FT /evidence="ECO:0000259|PROSITE:PS50069"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 395..420
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EJK74619.1"
SQ SEQUENCE 531 AA; 58722 MW; B2741AC4BC8F6C96 CRC64;
PPSSGPGASA PSGPGARDAE RRVVPDLLSF RTHLRRVHAE AFRSDDAFAS TVRSVLDDVV
NGNVPGSDDD GGRRTAELLA KHIDARFKDA RAAVSSSSSS SAGGLIDAAI AGDAAESFQA
EVMCLFRHVN SKDVFEAFYK RDLAKRLLTG RSVSYDMERS FLSKLKAECG AGYTSKMEGM
FKDMVRSLYF GFGPLQFFTN DRPHLPSSGA SPFSLPFPGS VPRDHNQLRR VRLPARATGG
LLRRLAVPQA GRVRRPGPDH GILACVPQVS QHRPPPRHRL GPVTVREILR QQVPGEADRL
AVLPRELRRE GDVPEVRCPE GAVGEPAAGA WLEHRSSLVL LCFQNDDGED GAGLTIDEIS
KRTGIDDRGE LTRVLQSLSM GREGTRVLRK IDHVQEATAD SGKPAPPSDS PRKKQKVRRT
VGPLDRFRFN ASFTSNQRRI RITNITMKET TEERKKTHDS VSKDRLYFID AAVVRIMKAR
KTVDHRDLMG EVLAQLKFPA SSSDIKKRIE SLIEREYMER VDGVSRYKYL A
//
