ID   K0TQ37_THAOC            Unreviewed;       905 AA.
AC   K0TQ37;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   RecName: Full=Helicase C-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=THAOC_02911 {ECO:0000313|EMBL:EJK75367.1};
OS   Thalassiosira oceanica (Marine diatom).
OC   Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC   Coscinodiscophyceae; Thalassiosirophycidae; Thalassiosirales;
OC   Thalassiosiraceae; Thalassiosira.
OX   NCBI_TaxID=159749 {ECO:0000313|EMBL:EJK75367.1, ECO:0000313|Proteomes:UP000266841};
RN   [1] {ECO:0000313|EMBL:EJK75367.1, ECO:0000313|Proteomes:UP000266841}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCMP1005 {ECO:0000313|EMBL:EJK75367.1,
RC   ECO:0000313|Proteomes:UP000266841};
RX   PubMed=22835381; DOI=10.1186/gb-2012-13-7-r66;
RA   Lommer M., Specht M., Roy A.S., Kraemer L., Andreson R., Gutowska M.A.,
RA   Wolf J., Bergner S.V., Schilhabel M.B., Klostermeier U.C., Beiko R.G.,
RA   Rosenstiel P., Hippler M., Laroche J.;
RT   "Genome and low-iron response of an oceanic diatom adapted to chronic iron
RT   limitation.";
RL   Genome Biol. 13:R66-R66(2012).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EJK75367.1}.
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DR   EMBL; AGNL01002971; EJK75367.1; -; Genomic_DNA.
DR   AlphaFoldDB; K0TQ37; -.
DR   EnsemblProtists; EJK75367; EJK75367; THAOC_02911.
DR   eggNOG; KOG0387; Eukaryota.
DR   Proteomes; UP000266841; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR   CDD; cd18793; SF2_C_SNF; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR038718; SNF2-like_sf.
DR   InterPro; IPR049730; SNF2/RAD54-like_C.
DR   InterPro; IPR000330; SNF2_N.
DR   PANTHER; PTHR45629:SF7; DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED; 1.
DR   PANTHER; PTHR45629; SNF2/RAD54 FAMILY MEMBER; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF00176; SNF2-rel_dom; 2.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000266841}.
FT   DOMAIN          306..472
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          557..717
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          120..145
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          168..248
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        9..25
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        188..230
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   905 AA;  100178 MW;  2FB24A08C99D9FEE CRC64;
     MRPGTKSPEL AQRTERSKMG DGAEEVQLLD VDSVDSSLYI VSPGPRFSTG TASSYNPPIQ
     VLAAFRDADN TLADAVVDYQ NLASAQGNRG KPLLSQSDQY CSPGSDVSCD LLSPIPTPNF
     QRIASPGFRG RGPPTPKSSL KSTALFPLEE NNVSVDMSRL SLKNTICEDE DNDDESDSDG
     SVEVQPPSKA HWKRRVLVDD SDDSSEGDAL NESRCSSEED EFRQEGKARQ SFIYESDSSQ
     GEIEEGEADE SMVQFDGCGC WAIDDDSGDL YLAENPDEDW PRVRMPLSLY TNLYQHQRIG
     VQWMASLHDN VIKGGILADD MGMGKTYQVL SHIGSLMRGQ SIANSVIVAP KSVIQNWERE
     ANLIVKKECV QGVTISAITS EMKKATREKI LAQSFAASKK RPHVVIITYG LVSNHIGLLT
     TLQKDHPDSY WDYVILDEDV IEASRQRDAS SWTVKKGKEM TEALKKKLEP YFLQRLKKTE
     FGGDGLPTKE EICVFCDLSK RQREIYAEYT KNGFDAEQHG SPLSAITWLK MLCGHPLLVK
     KHQDSSDLLE GSAKLQVLLS LLLRLQRSNH RTLVFSQSTK MLDIIERVLD GEDIKMRRID
     GSTGQSDRQK TVDSFNDVES DVGVLLLSTK ACGVGLTLTG ADRAILFDIS WNPSEDSQAV
     DRCYRIGQKK PVKVYRLLTA GTVEEKIYER QVHKNGIRQE ILSSDSTARY FNSDDLADLF
     TLGKAGECKT LKKFHAKQLP ASTKAGVAKR SFLSRDPNVV GVANHDDLYE SDVIRVDLPA
     TGDPFSKSPF RREGLKKRSV IFLPVKDHSG GGNEPEEVNS PKKMQLEGAS DIATKTNAVE
     VTPTRHKAKV LDKLLRLVDE KGDQLKGPEK LDVHRRIAEI GVSFGWLDTK VAAFAAPKEC
     ESSIG
//