ID K0UAN6_MYCVA Unreviewed; 1638 AA.
AC K0UAN6;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 24-JAN-2024, entry version 58.
DE SubName: Full=P-type HAD superfamily ATPase {ECO:0000313|EMBL:EJZ04402.1};
GN ORFNames=MVAC_29033 {ECO:0000313|EMBL:EJZ04402.1};
OS Mycolicibacterium vaccae ATCC 25954.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=1194972 {ECO:0000313|EMBL:EJZ04402.1, ECO:0000313|Proteomes:UP000006072};
RN [1] {ECO:0000313|EMBL:EJZ04402.1, ECO:0000313|Proteomes:UP000006072}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25954 {ECO:0000313|EMBL:EJZ04402.1,
RC ECO:0000313|Proteomes:UP000006072};
RX PubMed=23105074; DOI=10.1128/JB.01462-12;
RA Ho Y.S., Adroub S.A., Abadi M., Al Alwan B., Alkhateeb R., Gao G.,
RA Ragab A., Ali S., van Soolingen D., Bitter W., Pain A., Abdallah A.M.;
RT "Complete Genome Sequence of Mycobacterium vaccae Type Strain ATCC 25954.";
RL J. Bacteriol. 194:6339-6340(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216;
CC Evidence={ECO:0000256|ARBA:ARBA00001836};
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJZ04402.1}.
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DR EMBL; ALQA01000121; EJZ04402.1; -; Genomic_DNA.
DR RefSeq; WP_003934045.1; NZ_JH814710.1.
DR PATRIC; fig|1194972.3.peg.5752; -.
DR eggNOG; COG0474; Bacteria.
DR HOGENOM; CLU_002360_0_1_11; -.
DR Proteomes; UP000006072; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 2.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 1.20.1110.10; Calcium-transporting ATPase, transmembrane domain; 2.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 2.
DR InterPro; IPR006068; ATPase_P-typ_cation-transptr_C.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01494; ATPase_P-type; 2.
DR PANTHER; PTHR42861; CALCIUM-TRANSPORTING ATPASE; 1.
DR PANTHER; PTHR42861:SF29; SECRETORY PATHWAY CALCIUM ATPASE, ISOFORM G; 1.
DR Pfam; PF00689; Cation_ATPase_C; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR PRINTS; PR00120; HATPASE.
DR SFLD; SFLDG00002; C1.7:_P-type_atpase_like; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 1251..1390
FT /note="Cation-transporting P-type ATPase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00689"
FT REGION 1431..1456
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1564..1638
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1588..1638
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1638 AA; 168726 MW; 90972C7C98C602DE CRC64;
MTVNLLNAPF QAAQTVLGVV REAAGGHPVR RSSSAGRTRW IEVRGLGTED GSRIGAAVLA
AVRAEAGVRA AALNVANSRV VVTVSEAGPG AAHLCRVVDD AEAGAQATTE RTRPVTLPGD
DELLAERLLA AAVSAAGIGP AVIGAVLGAG RFGNAVSLPG AFAEYFPLVR NQFERHLGRD
ATDLSVTVLG TAAGVLTASP AAVVHQTATR VMRAAEAINV RRSWQRSEPE IREQAIKFAD
QSGVVPRDVD QFDAGGAGVR YADRAAEIGL GAAALLGVAS RDRETASAAA LVATARPVRS
ITEAFACALG RGLTEHHGAL VLRPVVLRRL DQIDTVVIDP RILYTDELAV TRVQGVDNGD
RGVAWQAARA ALADGALAPG WSPLAGIPGA GRSGEVLVSA IRDPWASALV TESRRAGARV
VSLDDEGLRS LGQGFDDLRP ATGGVDRALA DTVAELSAGG ARIALLTAST GLASTKAHVT
VGVWRNGSPP PWDADILVPD LTGVWRVVHA LPAARHTVVR GIEMSASASA LGAVMLLPSV
LGSGPVAGSV TATAALWAGY RRGEQVFDEA LPHPEPGHDW HALPVDEVQL LLPRTQSSSG
SSADFGPDLP EGLRPFTAAA ARSWGLVSDF AGVVREDLAD PITTILATGA AATALLGSPL
DAMMVAAVQL LNTAISAEQT LHAERILSGL LAVQEPLARR LTGAGRGSDY EDVRAADLVP
GDVIRVRAGE VIPADARIIA ADAAEADESA LTGESLPVAK HVDATPGAPL AERACMLYSG
TTLVAGRVTA VVTAVGPAAQ MNRVAAMTSR KARKVGLQAQ LSRITNRALP WSLAGGGVVG
VLSLLRGTPL HDAVAGGVAI AVAAVPEGLP LVVTLAQSAA ARRLTSSSVL IRNPRAVEAF
ARLDVVCFDK TGTLSENRLR VTSVQPLDGV DATQLLDAAV HTVRPTTGQH SDHATDDAVR
VAAADAGVFP GGTDARLPFQ SDRPYAAALI GTRLSVKGAP EAVTAALADG RAEVTRRIDD
MTAGGMRVLV VAERELTADQ AAAVAADPGA LADLCTSGMT PLGVIGMADT ARASARPLLE
ELQARGIGVR LITGDHPVTA AVVAGSLGLT VAADEVMTGP EWERLTTEDR VEAARTRRVF
ARMAPEHKVQ VVQALESADL VTAMVGDGAN DAAAIRAATV GVGVVSAGSD PARTAADVLL
LDGQIGALLS ALDEGQQLWQ RVSSAVSMLV GHNIGEVAFA LITSLLMGRP ALNARQILLI
NLLTDALPAA ALAVSPQTGD QITGERSEAA LWRAIWMRGA STATGGTLAW AFGRATGTPQ
RAATMGLIGL VLTQMGQTLT DSRGRLVVAT NVGTLAVMAG VISTPGLSQV FGCRPVGPIG
WAQAAAAAGI AGALPRLAPG ASERIAEAVR SLAEEAREKL SVVDLQQARA DQDGVDLTQR
RGQQSHAGGD QRVGPDRAWN LRHVGQANQP GFDSVRHLAR MEDEMWESAR SFVADHRDVS
KLVREAEKFS VQLPGIGRVR IPPPEQVAFY GVLGGLAAAQ LIDWPIALIV GLGHAVAARQ
GPDRGTEASL ESAPVTKAVT KAPAKKAPVK KAAAKKAPAK KTPVKKAAAK KTPVKKAAAK
KTPAKKAAAK KAPAKKTP
//
