GenomeNet

Database: UniProt
Entry: K0UFR4_MYCVA
LinkDB: K0UFR4_MYCVA
Original site: K0UFR4_MYCVA 
ID   K0UFR4_MYCVA            Unreviewed;       532 AA.
AC   K0UFR4;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   10-APR-2019, entry version 48.
DE   SubName: Full=Multi-sensor signal transduction histidine kinase {ECO:0000313|EMBL:EJZ05706.1};
GN   ORFNames=MVAC_24311 {ECO:0000313|EMBL:EJZ05706.1};
OS   Mycolicibacterium vaccae ATCC 25954.
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=1194972 {ECO:0000313|EMBL:EJZ05706.1, ECO:0000313|Proteomes:UP000006072};
RN   [1] {ECO:0000313|EMBL:EJZ05706.1, ECO:0000313|Proteomes:UP000006072}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25954 {ECO:0000313|EMBL:EJZ05706.1,
RC   ECO:0000313|Proteomes:UP000006072};
RX   PubMed=23105074; DOI=10.1128/JB.01462-12;
RA   Ho Y.S., Adroub S.A., Abadi M., Al Alwan B., Alkhateeb R., Gao G.,
RA   Ragab A., Ali S., van Soolingen D., Bitter W., Pain A., Abdallah A.M.;
RT   "Complete Genome Sequence of Mycobacterium vaccae Type Strain ATCC
RT   25954.";
RL   J. Bacteriol. 194:6339-6340(2012).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC         histidine.; EC=2.7.13.3;
CC         Evidence={ECO:0000256|SAAS:SAAS01126420};
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EJZ05706.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; ALQA01000073; EJZ05706.1; -; Genomic_DNA.
DR   STRING; 1194972.MVAC_24311; -.
DR   EnsemblBacteria; EJZ05706; EJZ05706; MVAC_24311.
DR   PATRIC; fig|1194972.3.peg.4842; -.
DR   Proteomes; UP000006072; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd00075; HATPase_c; 1.
DR   CDD; cd00082; HisKA; 1.
DR   Gene3D; 3.30.565.10; -; 1.
DR   InterPro; IPR007891; CHASE3.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR003661; HisK_dim/P.
DR   InterPro; IPR036097; HisK_dim/P_sf.
DR   InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR   Pfam; PF05227; CHASE3; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF00512; HisKA; 1.
DR   PRINTS; PR00344; BCTRLSENSOR.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00387; HATPase_c; 1.
DR   SMART; SM00388; HisKA; 1.
DR   SUPFAM; SSF47384; SSF47384; 1.
DR   SUPFAM; SSF55874; SSF55874; 1.
DR   PROSITE; PS50885; HAMP; 1.
DR   PROSITE; PS50109; HIS_KIN; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|SAAS:SAAS00925949};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000006072};
KW   Kinase {ECO:0000256|SAAS:SAAS01003914, ECO:0000313|EMBL:EJZ05706.1};
KW   Membrane {ECO:0000256|SAAS:SAAS00925724, ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000256|SAAS:SAAS00925310};
KW   Transferase {ECO:0000256|SAAS:SAAS01003669};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00926038,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00926160,
KW   ECO:0000256|SAM:Phobius};
KW   Two-component regulatory system {ECO:0000256|SAAS:SAAS00924981}.
FT   TRANSMEM     21     42       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    196    216       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      218    270       HAMP. {ECO:0000259|PROSITE:PS50885}.
FT   DOMAIN      299    519       Histidine kinase. {ECO:0000259|PROSITE:
FT                                PS50109}.
FT   COILED       92    126       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   532 AA;  58099 MW;  4CFDA216944B85F1 CRC64;
     MSGGRRRRDI AAGLTVQGWQ YVVLSVMGLV VLVGGISVAV LLNRTDQVSS QLINHIQPAR
     VAAYQLQAAL RDQETAVRGY LIAADRQFLL PYEEGRVTEQ EAAAEIRQLE QDRPDLLADL
     DAIEQASGAW RTQYAEPVIA NVRPGVPGAV DPALTEIGKT DFDVLRGLFA TQNERLSQAR
     DGDVAELERV RTLRNAVLLA IAATFAATIV ALAVVLRRSL VRPLAVLAAA CRRVAQGKFG
     ERILAQGPKD IRAIAGDVEN MRQRIVDELE ASREATEALD VHAEELRRSN AELEQFAYVA
     SHDLQEPLRK VASFCQLLEK RYGDQLDERG TEYIGFAVDG AKRMQVLIND LLTFSRVGRL
     NSTETEVDLD KTLDTALSNL SAAVEESGAV IERPADGLPS LKGDPTLFTM LWQNLIGNAV
     KFHRDGVAPH IVIDVARDTD GETDTWSFTV TDNGIGIAPE FVDKVFVIFQ RLHGRDAYSG
     TGIGLALCKK IVEHHGGAIW IDTSYTDGTR FRFTLPITAD DTAPAALEGS TP
//
DBGET integrated database retrieval system