ID K0ULJ8_MYCVA Unreviewed; 444 AA.
AC K0ULJ8;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Cyclopropane-fatty-acyl-phospholipid synthase {ECO:0000313|EMBL:EJZ08017.1};
GN ORFNames=MVAC_16946 {ECO:0000313|EMBL:EJZ08017.1};
OS Mycolicibacterium vaccae ATCC 25954.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=1194972 {ECO:0000313|EMBL:EJZ08017.1, ECO:0000313|Proteomes:UP000006072};
RN [1] {ECO:0000313|EMBL:EJZ08017.1, ECO:0000313|Proteomes:UP000006072}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25954 {ECO:0000313|EMBL:EJZ08017.1,
RC ECO:0000313|Proteomes:UP000006072};
RX PubMed=23105074; DOI=10.1128/JB.01462-12;
RA Ho Y.S., Adroub S.A., Abadi M., Al Alwan B., Alkhateeb R., Gao G.,
RA Ragab A., Ali S., van Soolingen D., Bitter W., Pain A., Abdallah A.M.;
RT "Complete Genome Sequence of Mycobacterium vaccae Type Strain ATCC 25954.";
RL J. Bacteriol. 194:6339-6340(2012).
CC -!- SIMILARITY: Belongs to the CFA/CMAS family.
CC {ECO:0000256|ARBA:ARBA00010815}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJZ08017.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ALQA01000036; EJZ08017.1; -; Genomic_DNA.
DR RefSeq; WP_003931815.1; NZ_JH814694.1.
DR AlphaFoldDB; K0ULJ8; -.
DR PATRIC; fig|1194972.3.peg.3383; -.
DR eggNOG; COG2230; Bacteria.
DR HOGENOM; CLU_026434_6_2_11; -.
DR Proteomes; UP000006072; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008610; P:lipid biosynthetic process; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR003333; CMAS.
DR InterPro; IPR020803; PKS_MeTfrase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR43667; CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE; 1.
DR PANTHER; PTHR43667:SF1; CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE; 1.
DR Pfam; PF02353; CMAS; 1.
DR PIRSF; PIRSF003085; CMAS; 1.
DR SMART; SM00828; PKS_MT; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 172..424
FT /note="Polyketide synthase methyltransferase"
FT /evidence="ECO:0000259|SMART:SM00828"
SQ SEQUENCE 444 AA; 49218 MW; 50C8FA03A265CA33 CRC64;
MTTFRTRSHT GANDPALPGD RKLTLAEVLE IFAGGRRPLK FTAYDGSSAG PEDATLGLDL
LSPRGTTYLA TAPGDLGLAR AYVAGDLRLA GVHPGDPYDL LNALTERLEY KRPPARVLAN
VVRSIGIEHL KPIAPPPQEA LPRWRRIAEG LRHSKTRDAD AIHHHYDVSN TFYEWVLGPS
MTYTCACYPH PDATLEEAQE NKYRLVFEKL RLKPGDRLLD VGCGWGGMVR YAARHGVKAV
GVTLSREQAQ WARAAIERDG LGDLAEVRHG DYRDVLESHF DAVSSIGLTE HIGVANYPSY
FRFLKSKLRP GGLLLNHCIT RHHNRSHATA GGFIDRYVFP DGELTGSGRI ITEVQDVGLE
VVHEENLRMH YAMTLRDWSR NLVEHWDDAV AEVGLPTAKV WGVYIAASRV GFEQNAIQLH
QVLAVKLDER GGDGGLPLRP WWAA
//
