ID K0URP3_MYCVA Unreviewed; 1020 AA.
AC K0URP3;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Adenylyl cyclase class-3/4/guanylyl cyclase {ECO:0000313|EMBL:EJZ07705.1};
GN ORFNames=MVAC_18015 {ECO:0000313|EMBL:EJZ07705.1};
OS Mycolicibacterium vaccae ATCC 25954.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=1194972 {ECO:0000313|EMBL:EJZ07705.1, ECO:0000313|Proteomes:UP000006072};
RN [1] {ECO:0000313|EMBL:EJZ07705.1, ECO:0000313|Proteomes:UP000006072}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25954 {ECO:0000313|EMBL:EJZ07705.1,
RC ECO:0000313|Proteomes:UP000006072};
RX PubMed=23105074; DOI=10.1128/JB.01462-12;
RA Ho Y.S., Adroub S.A., Abadi M., Al Alwan B., Alkhateeb R., Gao G.,
RA Ragab A., Ali S., van Soolingen D., Bitter W., Pain A., Abdallah A.M.;
RT "Complete Genome Sequence of Mycobacterium vaccae Type Strain ATCC 25954.";
RL J. Bacteriol. 194:6339-6340(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJZ07705.1}.
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DR EMBL; ALQA01000040; EJZ07705.1; -; Genomic_DNA.
DR AlphaFoldDB; K0URP3; -.
DR PATRIC; fig|1194972.3.peg.3588; -.
DR eggNOG; COG2114; Bacteria.
DR eggNOG; COG3899; Bacteria.
DR HOGENOM; CLU_004435_0_0_11; -.
DR Proteomes; UP000006072; Unassembled WGS sequence.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR16305:SF28; ADENYLATE CYCLASE 10; 1.
DR PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SMART; SM00044; CYCc; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE 4: Predicted;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 11..141
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
SQ SEQUENCE 1020 AA; 110181 MW; DAA9A48F57343895 CRC64;
MSAVPEYKNV TVLFADVTRS MDIASAVGPE RLREIMSELL DRSTRVVKRY GGAVEFIGDG
VMALFGAPLA MEDHALRACL TALAIQDEAR DLAEKVRVRD GMDFKVRVGL NSGQVIAGDI
GSDSPGYTVI GEHVGLAQRM ESVAPPGGVM VSETTARLVE HDAQLGGVEW VHIKGANRPV
PARTLLGAAE RAQLRSADTP FVGRTSEIAE LVGSLEDSSR GRGVVVRVVG TPGIGKSRLA
RELAALATDR GMQVFWTYCQ SHTCDVPFGA ATGLLRAFFG IEHVPAESAR AATRSALPDA
DPQDLLMLDD MLGIGDGRPP PEDVTPDARK RRLTALLDSA LLSRRQPTVY VVEDAHWIDA
ASEAMIADFL GTIADAAALV LITHRPDYHG ALARPADRTI ALAPLDYSSS SKLTVSLVGP
DTSVATLAQR ITDRAAGNPF FIEEMIRDLA ERRVLGGTRG AFTCQGDADI PVPASVQTTI
AARIDRLAPA AKRTLYAAAA IGSPFSRTLL DAVAGSSAID DLVDAELIAR VSTHPDQYAF
RHPLMRAVAY ESQLRAGRAE LHRRIAAEIE RTDPEGAAAN AALIATHLEA AGDLRAAFDR
HMAAGTWATH RDIAAARMSW QRAVAVADGL PEDEPDRLTM RIAARTWLAA TTWRVGGELA
DVGFDELRDL TQQAGDKRSL AIGMAGLIQM LNFHGRYTEA SRLASEQVEL LDAIGDRELA
VALIPMVGAI AKWDAGEMSA SLDLAQRSID DAAGDATMGN LVVGSPLALA LAMRASTRCC
LGISGWRQDF DDALSIARSV DKFTFSTVVM FKYVAIMNWA LVADDDALRD TAEALDIARR
FGDNLLLTNA EFTYGFILVR RRDTDRRLGF ELMAKSRQVA LEHRYTIIAA WCVDLEVAAE
SIRRRDYDTA VDLCRGVLAS EIRAGEGVNR GWSTTVLVDA LLARNREGDR EDAEKVVAEL
AATPTEPTFL YHELPLMRMR AMLAKADGDL HAYAELRDRY RAHAEEVGFD GHIALARAMA
//
