ID K0VID3_MYCVA Unreviewed; 483 AA.
AC K0VID3;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE SubName: Full=Aldehyde dehydrogenase {ECO:0000313|EMBL:EJZ10854.1};
GN ORFNames=MVAC_07864 {ECO:0000313|EMBL:EJZ10854.1};
OS Mycolicibacterium vaccae ATCC 25954.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=1194972 {ECO:0000313|EMBL:EJZ10854.1, ECO:0000313|Proteomes:UP000006072};
RN [1] {ECO:0000313|EMBL:EJZ10854.1, ECO:0000313|Proteomes:UP000006072}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25954 {ECO:0000313|EMBL:EJZ10854.1,
RC ECO:0000313|Proteomes:UP000006072};
RX PubMed=23105074; DOI=10.1128/JB.01462-12;
RA Ho Y.S., Adroub S.A., Abadi M., Al Alwan B., Alkhateeb R., Gao G.,
RA Ragab A., Ali S., van Soolingen D., Bitter W., Pain A., Abdallah A.M.;
RT "Complete Genome Sequence of Mycobacterium vaccae Type Strain ATCC 25954.";
RL J. Bacteriol. 194:6339-6340(2012).
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|RuleBase:RU003345}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJZ10854.1}.
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DR EMBL; ALQA01000012; EJZ10854.1; -; Genomic_DNA.
DR RefSeq; WP_003929553.1; NZ_JH814687.1.
DR AlphaFoldDB; K0VID3; -.
DR PATRIC; fig|1194972.3.peg.1584; -.
DR eggNOG; COG1012; Bacteria.
DR HOGENOM; CLU_005391_1_0_11; -.
DR Proteomes; UP000006072; Unassembled WGS sequence.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345}.
FT DOMAIN 12..477
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT COILED 67..94
FT /evidence="ECO:0000256|SAM:Coils"
FT ACT_SITE 246
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 483 AA; 49868 MW; E5B1F6040A1FCE4E CRC64;
MIDGLNFIGG AWVPAQSGRT FTRANPADPT DVIGTFPASG AEDVGNAVDA LEKAAPEWAA
TTPERRAAIL ESAAAHLEAR SAELIAELVR EEGKTVAEAT MEVGRTPSNL RFYAGEATRA
AGRTLPAAGD TLVYTVREPI GIVGAITPWN FPLNIPSRKL GPALAVGDPV LFKPSELTPL
MGQRLVEALL AGGLPPGALA LVQGDGTAGA AVAADERIAA VTFTGSTAVG RSIHATVGPH
RRVQLEMGGK NPVVVADDAD LDRAAGLIVK GAFGLSGQAC TGTSRVIATD ATHDALVERV
VARTEALRVG PGAMPGVDLG ALAADAQLDK FLRYVAAGLE EGATLRCGGT PVDVPGHPGG
FFVRPAVFTD TAPAMRIVTE EVFGPLLAFQ RAGSLTEAIE LANATEFGLS AAIVTRDLAT
AQQFARRSRT GLVKINQPTT GMAMNAPFGG YKASSTATFK EQAGASMMEF YLAEKTVYLD
PGC
//
