ID K0YMZ0_9ACTN Unreviewed; 549 AA.
AC K0YMZ0;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=alanine transaminase {ECO:0000256|ARBA:ARBA00026106};
DE EC=2.6.1.2 {ECO:0000256|ARBA:ARBA00026106};
GN ORFNames=HMPREF9451_00307 {ECO:0000313|EMBL:EJZ84703.1};
OS Slackia piriformis YIT 12062.
OC Bacteria; Actinomycetota; Coriobacteriia; Eggerthellales; Eggerthellaceae;
OC Slackia.
OX NCBI_TaxID=742818 {ECO:0000313|EMBL:EJZ84703.1, ECO:0000313|Proteomes:UP000006069};
RN [1] {ECO:0000313|EMBL:EJZ84703.1, ECO:0000313|Proteomes:UP000006069}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIT 12062 {ECO:0000313|EMBL:EJZ84703.1,
RC ECO:0000313|Proteomes:UP000006069};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Morotomi M., Walker B.,
RA Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A.,
RA Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J.,
RA McCowen C., Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Slackia piriformis YIT 12062.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the class-I pyridoxal-phosphate-dependent
CC aminotransferase family. {ECO:0000256|ARBA:ARBA00007441}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJZ84703.1}.
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DR EMBL; ADMD01000001; EJZ84703.1; -; Genomic_DNA.
DR AlphaFoldDB; K0YMZ0; -.
DR PATRIC; fig|742818.3.peg.342; -.
DR eggNOG; COG0436; Bacteria.
DR HOGENOM; CLU_017584_4_2_11; -.
DR InParanoid; K0YMZ0; -.
DR OrthoDB; 9763453at2; -.
DR Proteomes; UP000006069; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd00093; HTH_XRE; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR43488; GLUTAMATE-PYRUVATE AMINOTRANSFERASE ALAA; 1.
DR PANTHER; PTHR43488:SF2; GLUTAMATE-PYRUVATE AMINOTRANSFERASE ALAA; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF01381; HTH_3; 1.
DR SMART; SM00530; HTH_XRE; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000006069}.
FT DOMAIN 37..69
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
FT REGION 104..128
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 549 AA; 60832 MW; 8A0660FB6947AD7A CRC64;
MPNGSFSDRL KQSMESAGIK QADLIRLAEN QGKKLGKSQV SQYVSGKTIP RKDVLDVLAL
VLGVDRDWLL GGVGEQETAG RSQGVVAQGQ ETHVCTNAAS DALSAESDLR KRPSDAIPSS
SPSSDGIHLQ EAVLRTIDQR STVMGMREFK KSSKLDNVLY DVRGPVADEA ARMEGNGQHI
LKLNIGNPAP FGFRTPFEVV QDMRQQLPEC EGYSDSRGLF SARKAIMQYA QIKHIPNVGM
DDIYTGNGVS ELINLSMQAL LDSGDEVLIP SPDYPLWTAC VTLSGGTPVH YICDEEAEWY
PDIADIESKV TPRTKAIVII NPNNPTGAVY PREVLQEIVE VARRHQLIIF SDEIYDRLCM
DGVEHVSIAE LAPDLPCVTF SGLSKSHMIA GYRIGWMIFS GEKKCIEGFM LGVNMLSNMR
LCSNVPAQSI VQTALGGHQS VKDYVVPGGR VYEQRNFVYE ALCNMEGVSV VKPKAAFYIF
PKLDVKKFGI TDDEQFALDL LHQKKILITR GGGFNWHKPD HFRIVYLPRI EVLSQAMEEL
GDFLEHYHR
//
