ID K0YTF2_9ACTO Unreviewed; 328 AA.
AC K0YTF2;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=PNPLA domain-containing protein {ECO:0000259|PROSITE:PS51635};
GN ORFNames=HMPREF9240_01147 {ECO:0000313|EMBL:EJZ86773.1};
OS Winkia neuii BV029A5.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Winkia.
OX NCBI_TaxID=888439 {ECO:0000313|EMBL:EJZ86773.1, ECO:0000313|Proteomes:UP000006075};
RN [1] {ECO:0000313|EMBL:EJZ86773.1, ECO:0000313|Proteomes:UP000006075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BVS029A5 {ECO:0000313|EMBL:EJZ86773.1,
RC ECO:0000313|Proteomes:UP000006075};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Saerens B., Vaneechoutte M.,
RA Walker B., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA Larimer J., McCowen C., Montmayeur A., Murphy C., Neiman D., Pearson M.,
RA Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Actinomyces neuii subsp. anitratus BVS029A5.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJZ86773.1}.
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DR EMBL; AGWP01000005; EJZ86773.1; -; Genomic_DNA.
DR RefSeq; WP_004806853.1; NZ_JH815215.1.
DR AlphaFoldDB; K0YTF2; -.
DR PATRIC; fig|888439.3.peg.1151; -.
DR eggNOG; COG1752; Bacteria.
DR HOGENOM; CLU_047251_2_1_11; -.
DR OrthoDB; 5290098at2; -.
DR Proteomes; UP000006075; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 1.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR002641; PNPLA_dom.
DR PANTHER; PTHR14226:SF29; NEUROPATHY TARGET ESTERASE SWS; 1.
DR PANTHER; PTHR14226; NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER; 1.
DR Pfam; PF01734; Patatin; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR PROSITE; PS51635; PNPLA; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000006075}.
FT DOMAIN 5..165
FT /note="PNPLA"
FT /evidence="ECO:0000259|PROSITE:PS51635"
SQ SEQUENCE 328 AA; 35426 MW; 9CCC6EE9A3D116E3 CRC64;
MRISLVLGSG GARGWAHIGV IEEVERRGHT IVSIAGASMG ALVGGVYGTG KLPEVAQWAA
SLTRTDVVRL VDPALGSAGI VRGQKVLKKI EEIAGSARIE ELSIPFTAVA TDLLSQREIW
FQSGPLYPAI RASISIPTIF TPVLMGDRLL ADGGLVNPVP VEPTLAQVSD ATIAVNLYGH
PDAHPRDRLR KAIEAERQGS ALAKSINKGV TALTDNELFH KITRYFEEPQ KEECGQITEP
GNPEAGNDPQ ENWGPEKLPS GISTWQVADM SMTTMQELVY RYRAASNPVS ATIEIPIDKV
GTLEFYRAQE MMDYGRELAA GVLDELES
//
