ID   K0ZDB7_9ACTO            Unreviewed;       547 AA.
AC   K0ZDB7;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   RecName: Full=GAF domain-containing protein {ECO:0000259|SMART:SM00065};
GN   ORFNames=HMPREF9241_01450 {ECO:0000313|EMBL:EJZ85450.1};
OS   Schaalia turicensis ACS-279-V-Col4.
OC   Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC   Schaalia.
OX   NCBI_TaxID=883077 {ECO:0000313|EMBL:EJZ85450.1, ECO:0000313|Proteomes:UP000003994};
RN   [1] {ECO:0000313|EMBL:EJZ85450.1, ECO:0000313|Proteomes:UP000003994}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ACS-279-V-Col4 {ECO:0000313|EMBL:EJZ85450.1,
RC   ECO:0000313|Proteomes:UP000003994};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Saerens B., Vaneechoutte M.,
RA   Walker B., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA   Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA   Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA   Larimer J., McCowen C., Montmayeur A., Murphy C., Neiman D., Pearson M.,
RA   Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Actinomyces turicensis ACS-279-V-COL4.";
RL   Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EJZ85450.1}.
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DR   EMBL; AGWQ01000008; EJZ85450.1; -; Genomic_DNA.
DR   RefSeq; WP_006681649.1; NZ_JH815210.1.
DR   AlphaFoldDB; K0ZDB7; -.
DR   STRING; 883077.HMPREF9241_01450; -.
DR   PATRIC; fig|883077.3.peg.1460; -.
DR   eggNOG; COG2203; Bacteria.
DR   eggNOG; COG4585; Bacteria.
DR   HOGENOM; CLU_034370_1_0_11; -.
DR   Proteomes; UP000003994; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR   Gene3D; 1.20.5.1930; -; 1.
DR   Gene3D; 3.30.450.40; -; 2.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR   PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR   PANTHER; PTHR24421:SF37; SIGNAL TRANSDUCTION HISTIDINE-PROTEIN KINASE_PHOSPHATASE UHPB; 1.
DR   Pfam; PF13185; GAF_2; 2.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF07730; HisKA_3; 1.
DR   SMART; SM00065; GAF; 2.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 2.
PE   4: Predicted;
KW   Kinase {ECO:0000256|ARBA:ARBA00022777};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003994};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT   DOMAIN          21..156
FT                   /note="GAF"
FT                   /evidence="ECO:0000259|SMART:SM00065"
FT   DOMAIN          177..320
FT                   /note="GAF"
FT                   /evidence="ECO:0000259|SMART:SM00065"
SQ   SEQUENCE   547 AA;  58629 MW;  4001D110D9690C1F CRC64;
     MPWGSEHALV KAALDLTSTL DLRKALTSFV DQACKLTHAP YGALIVLDTW GEASQLIEHT
     SEALPHSPSM PEELISQIPA TGHLLINDMS ECEDIPPASI TSFLGVSVLI NEQVYGRLFL
     TDKNGGFTAS DADVLSMLAP AAGVAVENAH LYADSRRTER WISASQQLTT TMLEGTDEEE
     ALELIAQTVR EVSRADTAII VLPSVGDTWA AEIIDGYLAD TLLGVVFPPE GRAMSVLHEG
     TGMIVDSMAR AQTMRLPQLA AFGPALYAPL RSRGNSAGIL ILLRRIGQPE FDLSELSLAE
     SLASQAALAL ELASAKHAED VATLLDERDR IGRDLHDFAI QQLFATGMQL DAAKVEVESG
     HPNPEAITAT LDRALASIDE AVRQIRAIVH NLREPDKSVA LVERIRREAS LTRSFLGFAP
     SLLITLDGHA INEVADDEQL MIETIDNRID PDLGDDIVAI VREGLSNIAR HAHATAGSVT
     VDIMGTGENG HVTVSIADDG RGIDPNHTRN SGLSNMSERA RIRGGNFEQG IGIGGLGARI
     TFRAPLA
//