ID K1E069_9MICO Unreviewed; 547 AA.
AC K1E069;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=FAD-binding dehydrogenase {ECO:0000313|EMBL:EKA60426.1};
GN ORFNames=B277_13129 {ECO:0000313|EMBL:EKA60426.1};
OS Janibacter hoylei PVAS-1.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Intrasporangiaceae;
OC Janibacter.
OX NCBI_TaxID=1210046 {ECO:0000313|EMBL:EKA60426.1, ECO:0000313|Proteomes:UP000004474};
RN [1] {ECO:0000313|EMBL:EKA60426.1, ECO:0000313|Proteomes:UP000004474}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PVAS-1 {ECO:0000313|EMBL:EKA60426.1,
RC ECO:0000313|Proteomes:UP000004474};
RX PubMed=23144385; DOI=10.1128/JB.01728-12;
RA Pawar S.P., Dhotre D.P., Shetty S.A., Chowdhury S.P., Chaudhari B.L.,
RA Shouche Y.S.;
RT "Genome Sequence of Janibacter hoylei MTCC8307, Isolated from the
RT Stratospheric Air.";
RL J. Bacteriol. 194:6629-6630(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKA60426.1}.
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DR EMBL; ALWX01000060; EKA60426.1; -; Genomic_DNA.
DR AlphaFoldDB; K1E069; -.
DR STRING; 1210046.B277_13129; -.
DR PATRIC; fig|1210046.3.peg.2519; -.
DR eggNOG; COG3573; Bacteria.
DR Proteomes; UP000004474; Unassembled WGS sequence.
DR GO; GO:0033765; F:steroid dehydrogenase activity, acting on the CH-CH group of donors; IEA:UniProt.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR014614; KsdD_DH.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR PANTHER; PTHR43260; 3-KETOSTEROID-DELTA-1-DEHYDROGENASE; 1.
DR PANTHER; PTHR43260:SF1; KSDD-LIKE STEROID DEHYDROGENASE RV0785; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR PIRSF; PIRSF036654; UCP036654; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 2..527
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
SQ SEQUENCE 547 AA; 58919 MW; 45FFAA5FBE408C80 CRC64;
MGHGLAGLVA AAELADAGRK VLLVDQESEA NLGGQAHWSF GGLFFVDSPE QRRLGIKDSA
ELAHSDWMNT AGFDRDEDHW PRQWAQAYLD FAAGEKRSWL HQQGMRWFPI VGWAERGDGS
AHGHGNSVPR FHITWGTGPG VVAPFARRVA EAKERGLITY AHRHRVDEII VEGGAVVGVR
GARLADDGAE RGVATNRDSI GGFELRAPVV LVASGGIGGN HDLVRANWPE RLGAPPKHMV
TGVPAHVDGR MIGITEAAGG NLINRDRMWH YVEGIRNWDP IWAQHGIRIL PGPSSMWLDA
EGNRLPAPLL PGYDTLGTLE HLRATGHDHS WFITNRSIAG KEFALSGSEQ NQDLTGKEVA
GVIRKRSLAD VTPSMQAFLD QGADFVQADT VEQLVAKMNE LVEDGEPRLD PALVKKQVDE
RDAQLDNPYG KDAQIAAMRV ARSYVGDKIS KRAYPPHKLT DPKKGPLVGV KLHILSRKTL
GGFETDLSAR VLGSDGQPIP GLYAAGEAAG FGGGGVHGYR ALEGTFLGGC IFSGRTAGRA
MGAEIGD
//
