ID K1KHA4_9BURK Unreviewed; 668 AA.
AC K1KHA4;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 24-JAN-2024, entry version 56.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=HMPREF9465_01214 {ECO:0000313|EMBL:EKB31109.1};
OS Sutterella wadsworthensis 2_1_59BFAA.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sutterellaceae; Sutterella.
OX NCBI_TaxID=742823 {ECO:0000313|EMBL:EKB31109.1, ECO:0000313|Proteomes:UP000005835};
RN [1] {ECO:0000313|EMBL:EKB31109.1, ECO:0000313|Proteomes:UP000005835}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2_1_59BFAA {ECO:0000313|EMBL:EKB31109.1,
RC ECO:0000313|Proteomes:UP000005835};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Daigneault M., Strauss J.,
RA Allen-Vercoe E., Walker B., Young S.K., Zeng Q., Gargeya S., Fitzgerald M.,
RA Haas B., Abouelleil A., Alvarado L., Arachchi H.M., Berlin A.M.,
RA Chapman S.B., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Larimer J., McCowen C., Montmayeur A., Murphy C., Neiman D.,
RA Pearson M., Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Sutterella wadsworthensis 2_1_59BFAA.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKB31109.1}.
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DR EMBL; ADMG01000031; EKB31109.1; -; Genomic_DNA.
DR RefSeq; WP_005435117.1; NZ_JH815516.1.
DR AlphaFoldDB; K1KHA4; -.
DR STRING; 742823.HMPREF9465_01214; -.
DR PATRIC; fig|742823.3.peg.1206; -.
DR eggNOG; COG5002; Bacteria.
DR HOGENOM; CLU_410991_0_0_4; -.
DR OrthoDB; 8807260at2; -.
DR Proteomes; UP000005835; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43711:SF1; HISTIDINE KINASE 1; 1.
DR PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF13188; PAS_8; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000005835};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 242..265
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 453..663
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 302..336
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 668 AA; 74770 MW; 314A973D7EC3F2F1 CRC64;
MKMKFRTYVI AALATTALVP LIAWSLLQWS DIRSSLAKDD WEQRFFTGIG SAFLVERMKS
VDVFAAHVES ETAKRLRAGV TCASLEGFLA ELAAANPYIK SLKCTGADTP AARAARSGGT
AWRLEPGDDG GSLRFYRRIA DRADVVIEGT AERGELFRDI AAMYNMRGVR FVLLDEERRY
VWPVLGLSGR AVWDHALGRE GLIEEAGERF WMSANRFSHG APQWTMIALK PQEERVADRR
EMIGRTLLLA VLVLSLTAAA GFAAIRPLSR SMRRLRGDLD EASYGTPETT LASGPEEFLE
FQRAYRALRE KLDDRRRRLE ADNVRLEETV ERRSSELEAR ERLFAQVFDD IHEGMMLLDE
DWRLRYGNHA AGTLIGVDGM ARLAEVCRSG LERRSDGTAL VTIEAGGRSL VLECDAFPFG
AAADGLRSGC CVLFRDVTGR TEVERMKDDL ISIVAHELRT PLTACRLQLD LLVKENGPQS
AYAAMGEDLD HLGRIVDDWL SVARIDGGSY RVEPRIVQTM PLVTRAVRLV RSRHEFRFDY
DIAEEAECIR VDPSAFVELL VNLFTNACRH ARPGEEPRIE FRARVDEMLV VDVCDSGTGF
PEGEAEKLFD RFYQVEQGNK RRTGGTGLGL VICRAICRAH GGRIEALRLE GRTVFRITLP
MPSQTDGL
//
