ID K1LFN2_9LACT Unreviewed; 255 AA.
AC K1LFN2;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE RecName: Full=Serine aminopeptidase S33 domain-containing protein {ECO:0000259|Pfam:PF12146};
GN ORFNames=HMPREF9706_01664 {ECO:0000313|EMBL:EKB53406.1};
OS Facklamia hominis CCUG 36813.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Aerococcaceae; Facklamia.
OX NCBI_TaxID=883111 {ECO:0000313|EMBL:EKB53406.1, ECO:0000313|Proteomes:UP000004465};
RN [1] {ECO:0000313|EMBL:EKB53406.1, ECO:0000313|Proteomes:UP000004465}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCUG 36813 {ECO:0000313|EMBL:EKB53406.1,
RC ECO:0000313|Proteomes:UP000004465};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Huys G., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Goldberg J., Griggs A., Gujja S.,
RA Hansen M., Howarth C., Imamovic A., Larimer J., McCowen C., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Facklamia hominis CCUG 36813.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKB53406.1}.
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DR EMBL; AGZD01000013; EKB53406.1; -; Genomic_DNA.
DR RefSeq; WP_006908972.1; NZ_JH932292.1.
DR AlphaFoldDB; K1LFN2; -.
DR STRING; 883111.HMPREF9706_01664; -.
DR ESTHER; 9lact-k1lfn2; CarbLipBact_1.
DR PATRIC; fig|883111.3.peg.1683; -.
DR HOGENOM; CLU_076594_2_0_9; -.
DR OrthoDB; 9800213at2; -.
DR Proteomes; UP000004465; Unassembled WGS sequence.
DR GO; GO:0052689; F:carboxylic ester hydrolase activity; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR012354; Esterase_lipase.
DR InterPro; IPR022742; Hydrolase_4.
DR PANTHER; PTHR11614:SF121; CARBOXYLESTERASE; 1.
DR PANTHER; PTHR11614; PHOSPHOLIPASE-RELATED; 1.
DR Pfam; PF12146; Hydrolase_4; 1.
DR PIRSF; PIRSF017388; Esterase_lipase; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000004465}.
FT DOMAIN 25..236
FT /note="Serine aminopeptidase S33"
FT /evidence="ECO:0000259|Pfam:PF12146"
FT ACT_SITE 102
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR017388-1"
FT ACT_SITE 202
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR017388-1"
FT ACT_SITE 232
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR017388-1"
FT SITE 151
FT /note="Important for substrate specificity"
FT /evidence="ECO:0000256|PIRSR:PIRSR017388-3"
SQ SEQUENCE 255 AA; 28960 MW; 15BD413FB9BEFE1F CRC64;
MVQDNQQELP FKGAKYFAGP DHQVGVLLLH AYTGSTRDMN LLGRLLNRQG YSVLIPLFSG
HDTQDIRNVL NYSPRIWQQE AHSALEWLLQ QGFKQVFVFG LSMGGVLAGD LLSLHRYPLA
GGGVFNAPLV TKEPIDISQA FMNLGEKLAR IRGEQADYME EYDHILAGHW QQMAELEQIK
QEIQPRLPQV NLPFYIGQSG QDELIDPQDS YLLKAHLSQA EVDFHYFPYN THSIPTNPKR
HDFDQSVLAF LQALT
//
