ID K1LG74_9LACT Unreviewed; 256 AA.
AC K1LG74;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE SubName: Full=Sortase {ECO:0000313|EMBL:EKB53621.1};
GN ORFNames=HMPREF9707_01374 {ECO:0000313|EMBL:EKB53621.1};
OS Falseniella ignava CCUG 37419.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Aerococcaceae; Falseniella.
OX NCBI_TaxID=883112 {ECO:0000313|EMBL:EKB53621.1, ECO:0000313|Proteomes:UP000005147};
RN [1] {ECO:0000313|EMBL:EKB53621.1, ECO:0000313|Proteomes:UP000005147}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCUG 37419 {ECO:0000313|EMBL:EKB53621.1,
RC ECO:0000313|Proteomes:UP000005147};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Huys G., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Goldberg J., Griggs A., Gujja S.,
RA Hansen M., Howarth C., Imamovic A., Larimer J., McCowen C., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Facklamia ignava CCUG 37419.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKB53621.1}.
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DR EMBL; AGZE01000037; EKB53621.1; -; Genomic_DNA.
DR RefSeq; WP_006702009.1; NZ_JH932301.1.
DR AlphaFoldDB; K1LG74; -.
DR STRING; 883112.HMPREF9707_01374; -.
DR PATRIC; fig|883112.3.peg.1370; -.
DR eggNOG; COG3764; Bacteria.
DR HOGENOM; CLU_045680_4_2_9; -.
DR Proteomes; UP000005147; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd06165; Sortase_A; 1.
DR Gene3D; 2.40.260.10; Sortase; 1.
DR InterPro; IPR005754; Sortase.
DR InterPro; IPR042007; Sortase_A.
DR InterPro; IPR023365; Sortase_dom-sf.
DR NCBIfam; TIGR01076; sortase_fam; 1.
DR Pfam; PF04203; Sortase; 1.
DR SUPFAM; SSF63817; Sortase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000005147};
KW Thiol protease {ECO:0000256|ARBA:ARBA00022807};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 31..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 156
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR605754-1"
FT ACT_SITE 217
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR605754-1"
SQ SEQUENCE 256 AA; 28879 MW; 084294170A813E25 CRC64;
MSQKYKSRAE IHNSSRRSRK KPRKKRGFRR FLNFVGILLI LTGVGLLLLD PIKNHFIRER
TNMNTVANVS RDDIVRNNGA NVSFDWTNIS ALDARQVLMS NVNPEDLPVI GGVAMPELGM
NLPIYKGASQ EGMFYGAGTL YPEQEMGKSN YSIASHHSIH KDLLFAPLLH AEYGQKIYLT
DLEKIYEYEV TNIETVSPDR VDVTYPTEVP TITMITCDSG LVNRVIVQGT LKETYTINDA
PKESLDAFKI KQTVPE
//
