ID K1P5C0_CRAGI Unreviewed; 365 AA.
AC K1P5C0;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Low-density lipoprotein receptor-related protein 3 {ECO:0000313|EMBL:EKC18842.1};
GN ORFNames=CGI_10010730 {ECO:0000313|EMBL:EKC18842.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC18842.1};
RN [1] {ECO:0000313|EMBL:EKC18842.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC18842.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00059}.
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DR EMBL; JH818489; EKC18842.1; -; Genomic_DNA.
DR AlphaFoldDB; K1P5C0; -.
DR HOGENOM; CLU_759216_0_0_1; -.
DR InParanoid; K1P5C0; -.
DR CDD; cd00112; LDLa; 1.
DR Gene3D; 2.40.128.620; -; 1.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 1.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR023415; LDLR_class-A_CS.
DR InterPro; IPR042333; LDLRAD2.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR PANTHER; PTHR24652; LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR24652:SF67; LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF00057; Ldl_recept_a; 1.
DR SMART; SM00042; CUB; 1.
DR SMART; SM00192; LDLa; 1.
DR SUPFAM; SSF57424; LDL receptor-like module; 1.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 1.
DR PROSITE; PS01180; CUB; 1.
DR PROSITE; PS01209; LDLRA_1; 1.
DR PROSITE; PS50068; LDLRA_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00124};
KW Lipoprotein {ECO:0000313|EMBL:EKC18842.1};
KW Receptor {ECO:0000313|EMBL:EKC18842.1}.
FT DISULFID 38..65
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00059"
FT DISULFID 161..173
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 168..186
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 180..195
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
SQ SEQUENCE 365 AA; 37669 MW; C7C59F2FA1FBDD30 CRC64;
MAAVVSRDVF LLLLAVHILT LVAGAAQLYH VVNVDGTCSN LTLKELSSGK IESQNGSTYP
NGTNCQLTWN STAGTKTLVL VTFDLADAQN GSCVDRLEMY DPADEANTKQ TLCGTNATNQ
VFEFSVPIVT FSLVTDAASS HNGTGFAALV TSFSDASNGS CSGSKFICDT DRCISDSLEC
DGDKNCGDQS DESSCSITSS APSTANTTDQ SASSTTDTPS ASSSPATSSQ SAASSSQSPA
STSQSPISLP ASAPSSSLAL GDKAVLVIII LASATVVTII ITAIIYTVWC KNNSVHPDVE
SIEVKEAPVS SRAHRDGPTT SRAPPQPPTP KAAPKPKAPA PREPEASPAK KGQAKKGKML
KKDAW
//
