ID K1PG32_CRAGI Unreviewed; 835 AA.
AC K1PG32;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=G-protein coupled receptors family 2 profile 2 domain-containing protein {ECO:0000259|PROSITE:PS50261};
GN ORFNames=CGI_10001342 {ECO:0000313|EMBL:EKC22872.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC22872.1};
RN [1] {ECO:0000313|EMBL:EKC22872.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC22872.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; JH817162; EKC22872.1; -; Genomic_DNA.
DR AlphaFoldDB; K1PG32; -.
DR HOGENOM; CLU_340173_0_0_1; -.
DR InParanoid; K1PG32; -.
DR OMA; FMDVALN; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR CDD; cd15040; 7tmB2_Adhesion; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR InterPro; IPR000832; GPCR_2_secretin-like.
DR PANTHER; PTHR47767; ADHESION G PROTEIN-COUPLED RECEPTOR G7; 1.
DR PANTHER; PTHR47767:SF1; ADHESION G-PROTEIN COUPLED RECEPTOR G7; 1.
DR Pfam; PF00002; 7tm_2; 1.
DR PRINTS; PR00249; GPCRSECRETIN.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 539..782
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
SQ SEQUENCE 835 AA; 93243 MW; A1D67E7212A9A3B3 CRC64;
MKGNPELPDE EMFLPSASAN SDVYRCDIQR KGVGLVLSKT IYTIPNEKRV SIFHATVSMT
GSLSLQDALL EAYMSSPESL LGQSRREILS KIYSVSRDIR PVSGGQLGFI GITSIPLRKR
NALNFLLYFV GPNEEWKSAE AMNYLLKNIT ISARTMARSF DSRRRRRQAL SVDFNTFEIR
NEEYCTVGYS PDFQSTYNFK PVGNGSMTYS EELCITDSEP LLSGLCYTRT AAPAEIRNVT
VNPNCQFLLN PSFANMTALE KLSNVPTNDS NVEIVASDVA NLTSNSSDLT VEDVVFTSMV
LENVASISSI SEQTTSSVLQ TLSNILEAPE EILMNAHTLV SSTTRILESV ETITRNVVLN
GTEYRNYQKS FAVAVTDVTS EDSPVIGIQL KNVGIDVVLD NDTIGLINAE DSINITSFDT
AIILPKDLVQ GNNSRVIFTI FESTKIFQVR QMNKRYELNG KVASATLISN GKSVLDLGRN
FVRSLRIRYV DSGITLFMPL PVDGRQGVAK ERKWKMDSSY ASDVKGQSDI IDKDNTLALS
IITIIGLSLS IVGLGLTVLS FLLFKQLRKG RGQQTLLNLS LALLCSMVIF LAGMERTDSY
YGCITVAALM HYFLLVSFMW MLVEGFLQYL RFVRVLGTYV PRFILKASIP AWGLPLIPVV
SVLAVDYDLY RGGKYYCWMS PTPFYYAFLL PVALIIIVNC IVFALVLKTL LNRPKGLQSN
QSESKRAMMN LRAAVSIFIL LGLTWIFGIL AIEDARIVFS YIFTILTTFQ GFFIFILFVA
REKQLRTYWG KLCCKRFIDR QKKYKPTSAS HSSSQPLSKL SSHETASTEI FFSSK
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