ID K1PHC3_CRAGI Unreviewed; 632 AA.
AC K1PHC3;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Guanylate cyclase receptor-type gcy-1 {ECO:0000313|EMBL:EKC20958.1};
GN ORFNames=CGI_10004997 {ECO:0000313|EMBL:EKC20958.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC20958.1};
RN [1] {ECO:0000313|EMBL:EKC20958.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC20958.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR EMBL; JH817899; EKC20958.1; -; Genomic_DNA.
DR AlphaFoldDB; K1PHC3; -.
DR HOGENOM; CLU_432972_0_0_1; -.
DR InParanoid; K1PHC3; -.
DR OMA; WINDAYS; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd06352; PBP1_NPR_GC-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR001170; ANPR/GUC.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR44755:SF11; ATRIAL NATRIURETIC PEPTIDE RECEPTOR 3 ISOFORM X1; 1.
DR PANTHER; PTHR44755; NATRIURETIC PEPTIDE RECEPTOR 3-RELATED; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR PRINTS; PR00255; NATPEPTIDER.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Receptor {ECO:0000313|EMBL:EKC20958.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 50..406
FT /note="Receptor ligand binding region"
FT /evidence="ECO:0000259|Pfam:PF01094"
SQ SEQUENCE 632 AA; 70086 MW; 9AA9047E5B88B2A0 CRC64;
MTFREVLGTL VFNVFVTRAF SGNVQAVWMA PRVTPPGSAL AVNASTSVGA LAYAVDSIYR
NGILANGIFQ INWIDSGCDS KQSIGEFTDF LFNNRVDVIF GPPCTKAMIP IAELAAYRDI
PVFGWLSNEE SLDDKNKLQT LVRSIAPLSA IGSILSIFLS GFFWLRLIVI SSADSECEAY
ASAFISEIET PYWASYGFFL AHHYARVELN ATDSTIDTMY SAIKYEGRII IIIVPESELR
SYMVRAHAQG MDGGGYQFLF IKTTLVTSEE LADLESTALW ERGLPDDEGA RQGFENLLYL
SFGDTLQGNA TSSWINDAYS AYLSLKLSFP SLPDWAEPDI YSPALHDAVY LYAHALRDNG
GDPANVNGSL IKQAVENTHF KGLSGDVIMS NDADRYASIT VFDLTESGNF TTVAFYRMAI
VNGTIFPESD LTYFRWGDGT TSDDRIPEDT PRCGFFNEKC PPASASSDDL AVYIGVSLAV
MVLALMMFLA YRIWKREKDL QNVAWKIHFR DIDFLVGKQV RSFMNLSRHD TSSELATRKG
SAGESPLRHR RPSLGSRSDK ETEYNCGTTN ADTLSMDNNV VQSTNITVAR YRGRMVAIKS
LRKKKLKTDG VKFLKEMKQV RSCSLKGFVS VA
//
