ID K1PHW4_CRAGI Unreviewed; 223 AA.
AC K1PHW4;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 13-SEP-2023, entry version 32.
DE SubName: Full=Ganglioside GM2 activator {ECO:0000313|EMBL:EKC21148.1};
GN ORFNames=CGI_10004527 {ECO:0000313|EMBL:EKC21148.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC21148.1};
RN [1] {ECO:0000313|EMBL:EKC21148.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC21148.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JH815986; EKC21148.1; -; Genomic_DNA.
DR AlphaFoldDB; K1PHW4; -.
DR HOGENOM; CLU_1241192_0_0_1; -.
DR InParanoid; K1PHW4; -.
DR OMA; DINHTIF; -.
DR GO; GO:0008047; F:enzyme activator activity; IEA:InterPro.
DR GO; GO:0006689; P:ganglioside catabolic process; IEA:InterPro.
DR Gene3D; 2.70.220.10; Ganglioside GM2 activator; 1.
DR InterPro; IPR028996; GM2-AP.
DR InterPro; IPR036846; GM2-AP_sf.
DR InterPro; IPR003172; ML_dom.
DR PANTHER; PTHR17357:SF0; GANGLIOSIDE GM2 ACTIVATOR; 1.
DR PANTHER; PTHR17357; GM2 GANGLIOSIDE ACTIVATOR PROTEIN; 1.
DR Pfam; PF02221; E1_DerP2_DerF2; 1.
DR SMART; SM00737; ML; 1.
DR SUPFAM; SSF63707; Ganglioside M2 (gm2) activator; 1.
PE 4: Predicted;
FT DOMAIN 55..207
FT /note="MD-2-related lipid-recognition"
FT /evidence="ECO:0000259|SMART:SM00737"
SQ SEQUENCE 223 AA; 24605 MW; A18B45FA6632D0BE CRC64;
MVMDSIVSRH ARPSVPYLTF KRPPAIFFNL TRNKMISLVV LFVAVFSVEA KHLVYRDCNS
SPNKIAHVTS AHLNPFPVVV PGDLTGDIVV QAPRLVEGNH YKLDVHIQKH ALFWITVPCI
SNVGSCSYNL CDLLGPNTTE CAPQLKSQNL PCHCPFQPGT YTLQPATFKV PEMSGIWSWL
ASGDYRVDAK ITDTNTGEEV ACYHVEVSAT QPPCSGFLCN IFG
//
