GenomeNet

Database: UniProt
Entry: K1PJU2_CRAGI
LinkDB: K1PJU2_CRAGI
Original site: K1PJU2_CRAGI 
ID   K1PJU2_CRAGI            Unreviewed;       688 AA.
AC   K1PJU2;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   11-DEC-2019, entry version 29.
DE   SubName: Full=Transcriptional regulator Erg {ECO:0000313|EMBL:EKC21903.1};
GN   ORFNames=CGI_10003121 {ECO:0000313|EMBL:EKC21903.1};
OS   Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC   Eukaryota; Metazoa; Lophotrochozoa; Mollusca; Bivalvia; Pteriomorphia;
OC   Ostreoida; Ostreoidea; Ostreidae; Crassostrea.
OX   NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC21903.1};
RN   [1] {ECO:0000313|EMBL:EKC21903.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC21903.1};
RX   PubMed=22992520; DOI=10.1038/nature11413;
RA   Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA   Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W.H., Paps J., Zhu Y.,
RA   Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA   Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA   Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA   Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA   Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA   Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA   Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA   Wang J., Wang Q., Steinberg C.E.W., Wang H., Li N., Qian L., Zhang G.,
RA   Li Y., Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT   "The oyster genome reveals stress adaptation and complexity of shell
RT   formation.";
RL   Nature 490:49-54(2012).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019,
CC       ECO:0000256|SAAS:SAAS00594387}.
CC   -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|RuleBase:RU004019,
CC       ECO:0000256|SAAS:SAAS00594391}.
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DR   EMBL; JH819184; EKC21903.1; -; Genomic_DNA.
DR   EnsemblMetazoa; EKC21903; EKC21903; CGI_10003121.
DR   InParanoid; K1PJU2; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 1.10.150.50; -; 1.
DR   InterPro; IPR000418; Ets_dom.
DR   InterPro; IPR035575; Fli-1.
DR   InterPro; IPR003118; Pointed_dom.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11849:SF161; PTHR11849:SF161; 1.
DR   Pfam; PF00178; Ets; 1.
DR   Pfam; PF02198; SAM_PNT; 1.
DR   PRINTS; PR00454; ETSDOMAIN.
DR   SMART; SM00413; ETS; 1.
DR   SMART; SM00251; SAM_PNT; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF47769; SSF47769; 1.
DR   PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR   PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR   PROSITE; PS50061; ETS_DOMAIN_3; 1.
DR   PROSITE; PS51433; PNT; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|RuleBase:RU004019, ECO:0000256|SAAS:SAAS00594397};
KW   Nucleus {ECO:0000256|RuleBase:RU004019, ECO:0000256|SAAS:SAAS00594400}.
FT   DOMAIN          368..454
FT                   /note="PNT"
FT                   /evidence="ECO:0000259|PROSITE:PS51433"
FT   DOMAIN          521..601
FT                   /note="ETS"
FT                   /evidence="ECO:0000259|PROSITE:PS50061"
FT   REGION          19..56
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          88..151
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          474..500
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        36..56
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        88..111
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        123..150
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   688 AA;  76492 MW;  B7BC928D4A733D7C CRC64;
     MACDVIKGGK SGRYSAYLEN HREDTVALPP RSRSVEERSS PGNNLESHQC SSVPAYLPNT
     EQCEQRETTE SCQQTQSLPI PALISERQGS QDSITQRVPT TAVQQAEGFQ QRPQIPPLIP
     TESLLRNENQ TPMAESSTTP PSNQDDESSA GAIDITDKGE THKASSNPMP SGANNLAVHN
     VSIPMPNTVG NIIATTRESG NLEDYSNRSI KSEPGIVTEP TCSMWGASTA YHVTSIDSTE
     LANMQQYLQY PAYGTRFDQP NQQTYETNAR CSSQEGVATS NTEDPMLPRE VGADMDDINN
     PFYTVPNYPN MFINQQSAYS SVPYGDTTQK QAQGAQSLPP YYESVKKVCE TKCIEETNVA
     SGRPKLEHDT DGVTMQTKKV IVPADPQTWS EGDVQQWLEW SRNEFKLRDM EVTRYHNIEG
     RQLCSMNKEQ FTHLFGPHNA ESLFSHLNFL RHGTAQVTSP NCIGPSVTSY VHGSGGSMKQ
     NTDPGFTKSA WSPQPSQSSQ DPYTLLGPLV GRLSSTGSGQ IQLWQFLLEL LSDRRNGTCI
     AWEGSNGEFK LVDPDEVARR WGERKSKPNM NYDKLSRALR YYYDKNIMTK VHGKRYAYKF
     DFVGLTQAMT PSTPDTTAYR YQQDMFGMSG YSTPRLNYLH PHAPMPTTTA GFLTPPAPYW
     TTSTNNIFPN TLNHVMSGHP GSLPSFYS
//
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