ID   K1PPA8_CRAGI            Unreviewed;       122 AA.
AC   K1PPA8;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   SubName: Full=Cystatin-A3 {ECO:0000313|EMBL:EKC18300.1};
GN   ORFNames=CGI_10013715 {ECO:0000313|EMBL:EKC18300.1};
OS   Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC   Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX   NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC18300.1};
RN   [1] {ECO:0000313|EMBL:EKC18300.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC18300.1};
RX   PubMed=22992520; DOI=10.1038/nature11413;
RA   Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA   Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA   Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA   Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA   Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA   Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA   Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA   Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA   Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA   Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA   Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT   "The oyster genome reveals stress adaptation and complexity of shell
RT   formation.";
RL   Nature 490:49-54(2012).
CC   -!- SIMILARITY: Belongs to the cystatin family.
CC       {ECO:0000256|ARBA:ARBA00009403}.
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DR   EMBL; JH817593; EKC18300.1; -; Genomic_DNA.
DR   RefSeq; XP_011445121.1; XM_011446819.2.
DR   AlphaFoldDB; K1PPA8; -.
DR   GeneID; 105340650; -.
DR   KEGG; crg:105340650; -.
DR   HOGENOM; CLU_150234_0_0_1; -.
DR   InParanoid; K1PPA8; -.
DR   OrthoDB; 2965043at2759; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IEA:InterPro.
DR   Gene3D; 3.10.450.10; -; 1.
DR   InterPro; IPR000010; Cystatin_dom.
DR   InterPro; IPR046350; Cystatin_sf.
DR   InterPro; IPR018073; Prot_inh_cystat_CS.
DR   InterPro; IPR001713; Prot_inh_stefin.
DR   PANTHER; PTHR11414:SF21; CYSTATIN 14A, TANDEM DUPLICATE 1-RELATED; 1.
DR   PANTHER; PTHR11414; CYSTATIN FAMILY MEMBER; 1.
DR   Pfam; PF00031; Cystatin; 1.
DR   SUPFAM; SSF54403; Cystatin/monellin; 1.
DR   PROSITE; PS00287; CYSTATIN; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490}.
FT   DOMAIN          67..104
FT                   /note="Cystatin"
FT                   /evidence="ECO:0000259|Pfam:PF00031"
SQ   SEQUENCE   122 AA;  13644 MW;  83B036EAEC83C070 CRC64;
     MQTFVFAVVV LSVACLAESR RDRPVGGLGR TKNATPEIQQ LVDSVQDEII GQLPLGYDRE
     QPLQLHAVTY REQVVAGKNY FIKVETGFGR YLHVRIYKDL SGNASVSSVQ LQKSLADPIE
     YF
//