ID K1PPY1_CRAGI Unreviewed; 841 AA.
AC K1PPY1;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Ankyrin repeat and protein kinase domain-containing protein 1 {ECO:0000313|EMBL:EKC26292.1};
GN ORFNames=CGI_10014787 {ECO:0000313|EMBL:EKC26292.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC26292.1};
RN [1] {ECO:0000313|EMBL:EKC26292.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC26292.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR EMBL; JH818582; EKC26292.1; -; Genomic_DNA.
DR AlphaFoldDB; K1PPY1; -.
DR HOGENOM; CLU_338380_0_0_1; -.
DR InParanoid; K1PPY1; -.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR PANTHER; PTHR11640:SF162; LIMBIC SYSTEM-ASSOCIATED MEMBRANE PROTEIN; 1.
DR PANTHER; PTHR11640; NEPHRIN; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR SMART; SM00248; ANK; 3.
DR SMART; SM00409; IG; 4.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
DR PROSITE; PS50835; IG_LIKE; 4.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:EKC26292.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Transferase {ECO:0000313|EMBL:EKC26292.1}.
FT DOMAIN 162..241
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 384..474
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 535..616
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 637..702
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 841 AA; 92354 MW; 9E6CE45B87424170 CRC64;
MNTRRKSVAL QIPDFSKGSK AKDKDEVSIW TIVSTGNAEG LRQFIKANGH ASLSKRTGNF
RSPLGLAVYL ENPELVQIML ECDPKPDVNI ADKNGNTPLH EAVERGYLQI VKQLVNTGLC
KLELKNPQGY TPLMTAVYHD YEEIAESLIT ADGPGDSVKL SPNLTTFEVD AGEPLPLITC
SAQCEPACRY IWYQYYRTNT DRYRGSTAVL NLGNASSSDV GIYMCRASNN VIGDNFEGNV
TFELRVKYSR YSANQTMTCT YDCEIAAILT VFPPLCTDTG NKYSVYATNR KGNSSIKTTH
YSNTIAYEST TALRPVPSVA ATLPPNASSS KMNGPARIIM GSAIAFLVFK LKSKTKADSR
RSCKGSINQV FGTNFQNGIL GDGPDDSKME LSGKETGIEG VSVSWKCAVS ESNPAVNLTW
YNGSTEFTPD SKPVVTSTDG NFKTEQEWKF TYTRDYSGSN VSCVATGYKN KTVTKSKQLQ
VNFAPELEVK GKNLYLIDKN TMKCYIDEGA TLNLTCRMVA ASPMTSAEWE GRDGPEFSNI
LDKSANEGDN ITLNADILNA NPLPVKITWR KVGSAKVLST NLKLSLQNIR REQAGVYVVE
ATSLRMRENN TTEEVTGNTT VNVVVKYGPG DSVKLSPNLT TVEVDAGEPI PPIACSAVCH
PACNYAWYRY YRTNIRIRIT STAVLKLGNA SSTDVGIYMC EAIAYVIGKH LGANVTFELH
APEIKSVVIN EYRRNPYNDS FPITVTSIIR TYPNATITWG ISHEKSLSSF LPLDSRYSAN
QTMTCTYDCE ITAILTVFPP LCTDTGNKYS LYATNRKGNS TIKTTHYSVT VTSYPDGNVE
K
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