ID   K1PXN8_CRAGI            Unreviewed;      1544 AA.
AC   K1PXN8;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   SubName: Full=Pre-mRNA-splicing factor CWC22-like protein {ECO:0000313|EMBL:EKC26428.1};
GN   ORFNames=CGI_10016870 {ECO:0000313|EMBL:EKC26428.1};
OS   Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC   Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX   NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC26428.1};
RN   [1] {ECO:0000313|EMBL:EKC26428.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC26428.1};
RX   PubMed=22992520; DOI=10.1038/nature11413;
RA   Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA   Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA   Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA   Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA   Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA   Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA   Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA   Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA   Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA   Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA   Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT   "The oyster genome reveals stress adaptation and complexity of shell
RT   formation.";
RL   Nature 490:49-54(2012).
CC   -!- SUBCELLULAR LOCATION: Nucleus speckle {ECO:0000256|ARBA:ARBA00004324}.
CC   -!- SIMILARITY: Belongs to the CWC22 family.
CC       {ECO:0000256|ARBA:ARBA00006856}.
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DR   EMBL; JH818976; EKC26428.1; -; Genomic_DNA.
DR   RefSeq; XP_011417796.1; XM_011419494.2.
DR   GeneID; 105321235; -.
DR   KEGG; crg:105321235; -.
DR   HOGENOM; CLU_246687_0_0_1; -.
DR   InParanoid; K1PXN8; -.
DR   OMA; KDPIANS; -.
DR   OrthoDB; 1115942at2759; -.
DR   GO; GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   Gene3D; 1.25.40.180; -; 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR003891; Initiation_fac_eIF4g_MI.
DR   InterPro; IPR003890; MIF4G-like_typ-3.
DR   PANTHER; PTHR18034; CELL CYCLE CONTROL PROTEIN CWF22-RELATED; 1.
DR   PANTHER; PTHR18034:SF3; PRE-MRNA-SPLICING FACTOR CWC22 HOMOLOG; 1.
DR   Pfam; PF02847; MA3; 1.
DR   Pfam; PF02854; MIF4G; 1.
DR   SMART; SM00544; MA3; 1.
DR   SMART; SM00543; MIF4G; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS51366; MI; 1.
PE   3: Inferred from homology;
SQ   SEQUENCE   1544 AA;  179305 MW;  0813604E58AE7AFC CRC64;
     MPRREESDQR KRRKSESSSS GSSSSDSSES DSDSSSSSSS SAGDTKKNKN KPKQSGSGDD
     RSRQSSRLDD SGVKSSSSKR RQDSSSDDES KKKGRSSDNE RSRSQSNSRI KRQSRSPSIK
     QISSPAGSRA SSRSEHNTSR HSSSRRSTSR SSSQRGKERQ PSSSPRRPDE RPSSRSSQKE
     RKKPEKHVAR SPSSSPPRQL NEREEKQARS PSSSPPNNPE ERDRQERSPD TSQPSRSEEI
     RPIDASPEGR PPSEGDSRSP SHTPPRGDRY DMSKYQEESG GSESDVDRKS RKKKHDMRNF
     ESEPESGECT DSDNEKKLKS AVKRKMEEED RYRRRGGRRG SPDERDDRRR RYSPDRNRRN
     ERYRDDRRDG RRSPERRRDD RRRKSLDRER EERRRSPAQD RRKQRDSRQI DKDAGGDTGE
     GDKKERAPRK TKEEEVLALT TRTGGAYIPP ARLRAMQASI TDKSSEAYQR IAWEALKKSI
     NGLINKVNVS NLQFVVQELF QENIVRGRGL VARSVIQAQT ASPTFTHVYA ALVAVVNTKF
     PQIGELILRR LVIQFRRGFK RNDKTLCLSS TQFIAHLVNQ QVAHEVLALE ILTLLLETPT
     DDSVEVAVGF LKECGQKLTE VTPRGVTAIF ERLRNVLHEG KIDIRVQYMV EVMFAIRKDG
     FKDHQSVIQE LDLIAEEDQF THLLTLEDEG TTDDILNVFK VDPEYQANEE KYKELKREIL
     DEGSSDEESG SGSGSESDSE SEEGEGEEGE KQTIIDQTET NLIALRRTIY LTIQSALDFE
     ECAHKLLRLE LKPGQEIELC NMILDCCAQQ RTYEKFFGLL AQRFCMIDKK YIEPFQNMFR
     EQYETIHRLE TNKLRNVAKF FSHLLHTDAI SWEVLEVIKL NEDDTTSASR IFIKVLFQEL
     SEYLGLPKLN DRLKDPTLQP YFEGLLPRDN PKNTRFSINF FTTIGLGGLT DDLREHLKNV
     KKQVAQQQAE ESESSSSSSS DDSSSSSSSD SSSSSSDSSS DSSSEDEAPR RKKKQKSSNV
     DEGRDGKKLR KGYPNGDIRE KEKRKGRKDS PESLRSKRRG REESPENAKP RRRDRDDSPE
     NVRPPKRKGR ENSPENVPPP KRRGRKNSEE NVRQQRRGHE DSFENQKSKR RGRNGSPEEP
     QSKRRVPDKS PYNARSKGRA DEESPGNYRS SRRDGRQESP EIERTQRDAY RSDRYNDRYS
     QEDGERRRDR EDRNSRRKDR EDSEDERDTE KYSDRRGERR KDMYEEENYN RSSKGRSRRG
     EDQRNGRYAD NSDEDAYEKR QIKEEGNRRE RDQRENGYLD RSIERERERS RNRQSSRDRS
     RNKQRTPDRS RDRNTSPAVR QSRERQRKED SRDDRYQQDR ESERNRRHED RRNYSNSQDI
     SRRGYEEDDR EEKMLRRGDR EVSRNGRSRE EDKGSEKKKR YEEDRRKMIP YDEEERKRNR
     REDEDEKSRR NKGSSRQSVD SSSEDSDSSS DSSSSSSSDS SSDSSSSSSS PPRKRKHSDS
     ESENLKDSVK KRRGSLDHDN RLESKRDRPQ REGSVRSRER DRRR
//