ID K1Q035_CRAGI Unreviewed; 1298 AA.
AC K1Q035;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=FERM, RhoGEF and pleckstrin domain-containing protein 2 {ECO:0000313|EMBL:EKC24704.1};
GN ORFNames=CGI_10004385 {ECO:0000313|EMBL:EKC24704.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC24704.1};
RN [1] {ECO:0000313|EMBL:EKC24704.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC24704.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
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DR EMBL; JH816045; EKC24704.1; -; Genomic_DNA.
DR HOGENOM; CLU_261703_0_0_1; -.
DR InParanoid; K1Q035; -.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13193; FERM_C_FARP1-like; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR014847; FA.
DR InterPro; IPR041788; FARP1/FARP2/FRMD7_FERM_C.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR019747; FERM_CS.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR45858; FERM DOMAIN CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45858:SF5; MOESIN_EZRIN_RADIXIN HOMOLOG 1; 1.
DR Pfam; PF08736; FA; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR PRINTS; PR00935; BAND41.
DR SMART; SM00295; B41; 1.
DR SMART; SM01195; FA; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00660; FERM_1; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
SQ SEQUENCE 1298 AA; 141787 MW; 3BCE3570D8969492 CRC64;
MLVNLQTNEN YIKVKAPGLS LWEAAVYHLQ LVECDYFGLQ YEDSHGLKCW LDHDKPILKQ
LPSPDSPLEF LVKFYTPDPG MLDEFSRYLY GLQIKKDLAN GSMVCSENTA ALIASYIAQA
EIGDFIIEEY HDHSYLSMLG PFVPNQTEEM LKKVAEYHKQ HIGESPAEAE AGLLDTARKV
ETYGMKLCPA RDHEGVILSL AVAHLGILVF QQFTRINTFS WAKIRKLSFK RKRFLIKLHP
ETYVSGQKGY YKDTVEFFFD SRDCCKNFWK KCLEHHAFFR CHRIKPVPRN KTRLVSHGSS
FRYSGRTQKQ LMSYVRENPV VTPQFQRSVS GRISSSRSTS VTPKITAKAV IHTTPDTTNS
MGSRGSHTAG SDRVVSPTRS DHNDSHSLDS SLSGSRSLHS PRLDGGHREG TPGVDDYQEN
EDEAVRGARL LVTNAECLGT NSHVSSANQN VHDNGNLASV DADISGGGGG VNGGGSNVVC
TNGGAVTVNN SDKSVGGKSG DTSPSHDNTG VVTHLKDSRR VMFAEDTKSS SSSSSSSDFP
TEQKQITSQA GKFMITLKEE IPAGTCITVS MEMSPVKEVP DSMEESENSV NGDRTDHCVV
RANSEVQESA DLYEPSAASG CVETGSMMET SPHGASPEAE KSEISSPDDL IEDIPYYLER
RLYDNGVADK QEVKSPPFVR RGRSSTKRRP TNMQIEHVKV YEGGSQSRNE SPASGRSLSR
DKEASKSMSP VGRSVTSRSP STGHRYTSKS SLERSPSCNR KVEIVNVHKL PPRDSYSSVD
DTTSPTMEKD VIRHIQSRGI LGKSLSFRGE REVRTRTPNL NKSSSFHGEK DLKTKIPNGG
ATFIDELHRK VSEIGDQKAD KSKLETNPCE SEKMKTEKGE GLSSVGNNNG GQVPDPGTVE
SVGDLCGESS VGLKLTDSVS LCGSDRVSQG MDLPSQAAAY LILNKDPPAR KPKLKNITFS
TFKPMDDTTA PGCRPSSVVD SETDAKSDYG SLPSAKHADS KKPLQIPVQP EAMLFNPTNT
KVVPAEVEGK KMDRFYGPLR PRKVSFHRER GYKYSFESVN DPPAFALAEP IEDICLIDTT
DRGPSKSPST DVLDILEGLE DAELVESDTS ESCTSSLDSD GPSDHSSSDE ESHKHDEFLI
FAKSLADSGK ETTKDSGVGV DEGPVRSLSQ DDPASDGKRG TKKPSQEKVD EREPPNRRTL
VRQSPTDSSL SSIESDSDPD LSCKRHSLDP LDDLENPSIA EVNTSFSDSS SDGEREEGQK
TGGGFVIPTL TFSLPSSPDA SSGSPKENQD NEFGSTFC
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