ID K1Q0H7_CRAGI Unreviewed; 432 AA.
AC K1Q0H7;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Ankyrin repeat domain-containing protein 13C-B {ECO:0000313|EMBL:EKC27423.1};
DE SubName: Full=Ankyrin_rpt-contain_dom domain-containing protein {ECO:0000313|EnsemblMetazoa:G714.2:cds};
GN ORFNames=CGI_10025413 {ECO:0000313|EMBL:EKC27423.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC27423.1};
RN [1] {ECO:0000313|EMBL:EKC27423.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC27423.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
RN [2] {ECO:0000313|EnsemblMetazoa:G714.2:cds}
RP IDENTIFICATION.
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EnsemblMetazoa:G714.2:cds};
RG EnsemblMetazoa;
RL Submitted (AUG-2022) to UniProtKB.
CC -!- FUNCTION: Acts as a molecular chaperone for G protein-coupled
CC receptors, regulating their biogenesis and exit from the ER.
CC {ECO:0000256|ARBA:ARBA00037107}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004586}. Membrane
CC {ECO:0000256|ARBA:ARBA00004370}.
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DR EMBL; JH817025; EKC27423.1; -; Genomic_DNA.
DR RefSeq; XP_011437079.1; XM_011438777.2.
DR EnsemblMetazoa; G714.2; G714.2:cds; G714.
DR EnsemblMetazoa; G714.3; G714.3:cds; G714.
DR GeneID; 105335089; -.
DR KEGG; crg:105335089; -.
DR HOGENOM; CLU_026137_1_0_1; -.
DR OMA; YPMHQSV; -.
DR OrthoDB; 20116at2759; -.
DR Proteomes; UP000005408; Unplaced.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR021832; ANKRD13.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR PANTHER; PTHR12447; ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13; 1.
DR PANTHER; PTHR12447:SF25; ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13C; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF11904; GPCR_chapero_1; 1.
DR SMART; SM00248; ANK; 2.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Reference proteome {ECO:0000313|Proteomes:UP000005408}.
FT REPEAT 36..68
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
SQ SEQUENCE 432 AA; 49662 MW; 90A3EBF2C9D6A43F CRC64;
MADWEGYPLH ECVFHNDIRR LSQFLRVNDV SLKDMHGNTA LHLAVMLGRK DCIQLLLAHG
APVRVKNLQG WTPLAEAISF GSRQTIMCLL KKLRQQSKET LEERRPALIQ ALKDIGDFYV
ELKWDFQSWV PLVSRILPSD ICKIHKKGSC LRLDTTLVDF NDMRWERGDI TFVFDGDAPP
NKGLTVLDNK SHEFQRIRSE ESEQELEDEV DILMSSDIMA AQMSTKSITF SRAQSGWLFR
EDKTERVGEF EADFYAVNGL ILDSRKRREH LSPDDIQKNK AIMENLTKGN WNDCEFQRRP
SLPVPEESSV TWEEYIAEPA GSPPCLGRPW VAKGNTKSFK ATVAMSKNFP MSIDVLLDVL
EVIAPFKQFQ KLREFMTTKL PDGFPVKIEI PVFPTVTAKV TFTSFDWRDD IDDAMFVVPP
NYRENPNRFP DL
//
