ID   K1Q729_CRAGI            Unreviewed;       623 AA.
AC   K1Q729;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 54.
DE   SubName: Full=ABC transporter G family member 22 {ECO:0000313|EMBL:EKC29733.1};
GN   ORFNames=CGI_10013010 {ECO:0000313|EMBL:EKC29733.1};
OS   Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC   Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX   NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC29733.1};
RN   [1] {ECO:0000313|EMBL:EKC29733.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC29733.1};
RX   PubMed=22992520; DOI=10.1038/nature11413;
RA   Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA   Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA   Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA   Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA   Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA   Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA   Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA   Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA   Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA   Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA   Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT   "The oyster genome reveals stress adaptation and complexity of shell
RT   formation.";
RL   Nature 490:49-54(2012).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC       Eye pigment precursor importer (TC 3.A.1.204) subfamily.
CC       {ECO:0000256|ARBA:ARBA00005814}.
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DR   EMBL; JH817688; EKC29733.1; -; Genomic_DNA.
DR   AlphaFoldDB; K1Q729; -.
DR   HOGENOM; CLU_000604_57_10_1; -.
DR   InParanoid; K1Q729; -.
DR   OMA; STLCDMM; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   CDD; cd03213; ABCG_EPDR; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR013525; ABC2_TM.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR48041; ABC TRANSPORTER G FAMILY MEMBER 28; 1.
DR   PANTHER; PTHR48041:SF63; EARLY GENE AT 23, ISOFORM C; 1.
DR   Pfam; PF01061; ABC2_membrane; 1.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
SQ   SEQUENCE   623 AA;  70863 MW;  37E0957CCCE60E85 CRC64;
     MELDFRNLCV EVDKKLILNN VSGLACPGEL LAVMGPSGAG KSTLLNTLAG RTPLSSGTIS
     VNGHNITKDL RRKICYVLQQ DIFFSSLTLK ETLQFTARIR LPEKMSNEQI TSKVNEIIQD
     LDLSRCVDTI MGDVWVRGLS GGEKKRASIA CELITDPVTI LLDEPTSGLD YSTAFSLIEM
     LQTYARNHNK TVVATIHQPS SFIFYQFQKL LLISDGELAY FGDTDKVVEF FHKAGVPMAS
     HYNPADFILE KLKEDEKTRL KIISAMDQMR TSSNWSPKLK KSEQVCKEGE TDPAPSQEIM
     EQTYKDSVHV SLMELDKADN VSSSRTPLDD KKWPTGFLIQ YKQLTLRTFK TSKSQMFSRF
     KLIETVVLTA IVSLIWFQLP RTEETLRDRM GVLFYMSMHW GFTPLFDTVT AFPLERLVIN
     KERLAGWYRL SAYYLAKMTS ELVLILVQPL FFITVVYWSV GLNGVSSYFA TLGTLFIHAI
     TGQSVGLFIG IASMDIRKGM TQATIYIMAT MLLGGFYTRS LPFWLDWIKY VSFLQYTFSA
     MMCLEFNDGP DIRCAVRSTT SESQFGTCLY SNSTHIPSNE VLRFYGINLP YWAYILPLFV
     FILFFRISGY FMLRYKQKPS QTN
//