ID K1QBK9_CRAGI Unreviewed; 475 AA.
AC K1QBK9;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=IRF tryptophan pentad repeat domain-containing protein {ECO:0000313|EnsemblMetazoa:G23210.2:cds};
DE SubName: Full=Interferon regulatory factor 8 {ECO:0000313|EMBL:EKC26205.1};
GN ORFNames=CGI_10003270 {ECO:0000313|EMBL:EKC26205.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC26205.1};
RN [1] {ECO:0000313|EMBL:EKC26205.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC26205.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
RN [2] {ECO:0000313|EnsemblMetazoa:G23210.2:cds}
RP IDENTIFICATION.
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EnsemblMetazoa:G23210.2:cds};
RG EnsemblMetazoa;
RL Submitted (AUG-2022) to UniProtKB.
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DR EMBL; JH818616; EKC26205.1; -; Genomic_DNA.
DR RefSeq; XP_011412644.1; XM_011414342.2.
DR SMR; K1QBK9; -.
DR EnsemblMetazoa; G23210.2; G23210.2:cds; G23210.
DR GeneID; 105317636; -.
DR KEGG; crg:105317636; -.
DR HOGENOM; CLU_031544_2_0_1; -.
DR OMA; SSYEQYH; -.
DR OrthoDB; 3740806at2759; -.
DR Proteomes; UP000005408; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IEA:InterPro.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:UniProt.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:UniProt.
DR CDD; cd00103; IRF; 1.
DR Gene3D; 2.60.200.10; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR019817; Interferon_reg_fac_CS.
DR InterPro; IPR001346; Interferon_reg_fact_DNA-bd_dom.
DR InterPro; IPR019471; Interferon_reg_factor-3.
DR InterPro; IPR017855; SMAD-like_dom_sf.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11949; INTERFERON REGULATORY FACTOR; 1.
DR PANTHER; PTHR11949:SF53; INTERFERON REGULATORY FACTOR-3 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00605; IRF; 1.
DR Pfam; PF10401; IRF-3; 1.
DR PRINTS; PR00267; INTFRNREGFCT.
DR SMART; SM00348; IRF; 1.
DR SMART; SM01243; IRF-3; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00601; IRF_1; 1.
DR PROSITE; PS51507; IRF_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005408}.
FT DOMAIN 21..128
FT /note="IRF tryptophan pentad repeat"
FT /evidence="ECO:0000259|PROSITE:PS51507"
SQ SEQUENCE 475 AA; 54521 MW; 51FDE23866FD0EE0 CRC64;
MATEIDIRRF LEVTMDSGQT RQRMRPWLES KVESGQIPGL AWIDREKKIF RVPWKHGGKH
DWNEADSTIF KEWAIHTGRY REGVDHADWP TWKTRFRCAL NKLPDIQEMK DHNQLDGSDP
YRAYKFLSKE ELTEMKSNNK EYREVCTLNK ASSPKEITSS DVIVLSEVKP VSEMPNFPSD
LEDLMLEPIK SDPNLAPMIQ SELIPTPADN IKEEQGDEDM KDLCEEYTQM TTRGPTLPAL
ISPQTTPFLQ DPPDHEMEII LRYCQQQVCN YGVCSPYGCR LFYDPERNDQ FVDGAIKQEL
FGPDLFEQLQ FPTCETSNPG QREHTSQLLV ALDRGLLLEC HEGVIYATRK SRCVIFISSP
CINNGEPFKL ERNTKTAVYD FLQYFETALQ QYLTGAAKKP LAHFLVGFGQ KLTSNNIDLS
GLLISAQVFH SRAKHRLNQV ACTSPLSSSI KISLPDDYDR LLHFVKDRCH GQMET
//
