ID K1QHV0_CRAGI Unreviewed; 522 AA.
AC K1QHV0;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Putative cytochrome P450 CYP44 {ECO:0000313|EMBL:EKC33403.1};
GN ORFNames=CGI_10019908 {ECO:0000313|EMBL:EKC33403.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC33403.1};
RN [1] {ECO:0000313|EMBL:EKC33403.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC33403.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|ARBA:ARBA00001971};
CC -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
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DR EMBL; JH816185; EKC33403.1; -; Genomic_DNA.
DR RefSeq; XP_011425105.1; XM_011426803.2.
DR AlphaFoldDB; K1QHV0; -.
DR GeneID; 105326656; -.
DR KEGG; crg:105326656; -.
DR HOGENOM; CLU_001570_28_2_1; -.
DR InParanoid; K1QHV0; -.
DR OMA; TNGEEWY; -.
DR OrthoDB; 3059838at2759; -.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR CDD; cd11054; CYP24A1-like; 1.
DR Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR PANTHER; PTHR24279; -; 1.
DR PANTHER; PTHR24279:SF117; -; 1.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|RuleBase:RU000461}; Iron {ECO:0000256|RuleBase:RU000461};
KW Metal-binding {ECO:0000256|RuleBase:RU000461};
KW Monooxygenase {ECO:0000256|RuleBase:RU000461};
KW Oxidoreductase {ECO:0000256|RuleBase:RU000461}.
SQ SEQUENCE 522 AA; 60467 MW; E5E25AF8E3235FA3 CRC64;
MGRITVCSRS YFYNQSKIFS WQCRRCLSVA VADESHETRS NSSTQNVKPF KDIPGPKGLP
YLGTILQYRK GPFQRFTVDR YQDALISRYK EYGPIVKETI AGVTFVRIYD PDDVRTVFLN
EDKQPHVAPL LDTTKQYREQ RDLSPGLGNT NGEEWYRLRS AVQQMMMRPK AVTVYLPFVE
EVVDDFIARI KKIHNSDGTI ENFRLEAAKW NLESSGMTCF ETRLGCLVDS PTSHIMRMIS
SNNAIFELST KINFSVPFHK LLTTRLWQKL LDEEDYFFRN GQKLVDETIA KIDRLQKEGN
LKDGQFNFLL YLLSKKELSF KDVSIITLSL FGDGLNTTVP TLIFAMYCLA KNPDVQQKAY
EEIREVLKDD EPITGEHINR MPYLKACVKE SQRILPIGLE IKRILKKDLV LGNYLVPAGT
TVELAPYVHY MSSEYFVEPD RFLPERWLRD GSALNIHPYL LTPFGHGPRM CAGRRFAEQE
LYVLLSKMLK NFRLEYSGDL DMKFQVLMVP DRPTSFTFKD RL
//
