ID K1QIG4_CRAGI Unreviewed; 1261 AA.
AC K1QIG4;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 {ECO:0000313|EMBL:EKC28670.1};
GN ORFNames=CGI_10007173 {ECO:0000313|EMBL:EKC28670.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC28670.1};
RN [1] {ECO:0000313|EMBL:EKC28670.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC28670.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; JH817041; EKC28670.1; -; Genomic_DNA.
DR AlphaFoldDB; K1QIG4; -.
DR HOGENOM; CLU_252956_0_0_1; -.
DR InParanoid; K1QIG4; -.
DR OMA; NINDCHE; -.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00033; CCP; 2.
DR CDD; cd00054; EGF_CA; 2.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 2.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 1.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 2.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR003410; HYR_dom.
DR InterPro; IPR043555; SRPX-like.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR InterPro; IPR011641; Tyr-kin_ephrin_A/B_rcpt-like.
DR PANTHER; PTHR46343; HYR DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46343:SF2; SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1-LIKE; 1.
DR Pfam; PF00008; EGF; 2.
DR Pfam; PF07699; Ephrin_rec_like; 3.
DR Pfam; PF02494; HYR; 2.
DR Pfam; PF00084; Sushi; 2.
DR Pfam; PF00090; TSP_1; 1.
DR SMART; SM00032; CCP; 3.
DR SMART; SM00181; EGF; 5.
DR SMART; SM00179; EGF_CA; 2.
DR SMART; SM01411; Ephrin_rec_like; 4.
DR SMART; SM00209; TSP1; 1.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 2.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS00022; EGF_1; 2.
DR PROSITE; PS01186; EGF_2; 2.
DR PROSITE; PS50026; EGF_3; 2.
DR PROSITE; PS50825; HYR; 2.
DR PROSITE; PS50923; SUSHI; 3.
DR PROSITE; PS50092; TSP1; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302}.
FT DISULFID 267..294
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 797..807
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 818..827
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 856..865
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 1261 AA; 136460 MW; 974FEB085D76D995 CRC64;
MAFTLSSTKF RLLLGVCLCA ILINVAGIMS FGGGTEDKQT CRVSELDVNE KWDDDRLVQN
GDPFLYGDTI YTCVDGQWLN RDKVNIPPKF TSCPPSGVVI YADRLRTTAN HSWTQPTATD
REQGVLPVTL SFGKESGSEF DRGFQAITYE AVDDGGQRAI CSFSFTVKVT SCSPIKWPVN
GNVNCPPGEF LYGTTCNVTC QKGYEMVPMT NDGIQSITCH ANGHKNSLPN ICQLIECPSN
DPKLNPEHGT VSCTNSNYYN SLCTTKCKEG YTRKMETETV CGEDKTWSNK TPDCKDSQPP
LLKRCPENIY TYASKTGPSD PVTWASPLSE DNSGISFVNQ TVGPINGSSF PVGQTEIRYI
ASDLDGNVSP ECVFFVIVEE NPCNPLPSPL NGAMVCDTWL YGRFCQMQCT DKFDIPYGVA
GTNGGSFTGA YTCSDLQGTF TPSNVVANCT VRKNPRKTGI LGEFSYYTGD CNDATVLTDI
KTNFINLMQY QEKRGFAGVC PDETECNVNN TVVTCGPVSG RRKKRHTHEI GTYSGYNSMP
TDRTKRNTHE IRVETLLTTS WYNFNSSNVD TFYFLESLQT KLFDVIKDLG RNGSLTVRAL
SPDNNSFQLG YSDPFCDEGL AVRWSTLTCV PCSVGTYLDN TDPWTPKCYD CPKGTYKDTE
DALSCTSCPV GTSTLNQASI SENECIAQCK PGVYSVSGLV PCSPCPRSSY QSQSMSSTCL
ACPPGKSSKS GSTMLSECKG VAVSGYRLIT GVSSDSDVAQ LASMCNASLS SLIDLTIENL
IGASVAVPSV CYSTNHCNPN PCNGQICLSE AQSFVCQCEN GFTGDNCQNA PRLCSETTCD
NAGTCTNNGV NFTCICPTGY RGKRCEIQIV NGGWSEWNAW ASCSTTCNGG MKTRTRECKS
PPPDSDGIPC DSQFFSESVA CNTAPCPSCP ELPKSFGTKS NCSTNQDGNT ACSLSCRPGL
IFSIANPPLD EYICGPGTAY EWNGIPPACG RGHGPRNVQI KANVGYGRLI PCTKAASVAQ
SLKNNMQGGL QCRYNNICDV QVEISGCALY GRKRRSTRSS IVVTLSVTFT STDIDLTSYD
LYENMSQPLA ELFTAIDELS ASADQLNSSY SLLSFVVDGI TYTSSDVSLT DSVLCESTFG
TTDVLCVECP SGTYYLQGLC EVCPIGTYQD EMGKTYCKTC PSGYTTQFIA SQSPTACSVP
SSASTTENNI PIEDQHREKT QCNTSFERGG VRESLISEIE YSASNIYTEF AIGNYSSIGG
K
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