ID K1QJ88_CRAGI Unreviewed; 744 AA.
AC K1QJ88;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE SubName: Full=Signal transducing adapter molecule 2 {ECO:0000313|EMBL:EKC28935.1};
GN ORFNames=CGI_10016438 {ECO:0000313|EMBL:EKC28935.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC28935.1};
RN [1] {ECO:0000313|EMBL:EKC28935.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC28935.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
CC -!- SIMILARITY: Belongs to the STAM family.
CC {ECO:0000256|ARBA:ARBA00009666}.
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DR EMBL; JH816162; EKC28935.1; -; Genomic_DNA.
DR AlphaFoldDB; K1QJ88; -.
DR HOGENOM; CLU_373498_0_0_1; -.
DR InParanoid; K1QJ88; -.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-KW.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd21388; GAT_STAM; 1.
DR CDD; cd11820; SH3_STAM; 1.
DR CDD; cd03568; VHS_STAM; 1.
DR Gene3D; 1.20.5.1940; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR003903; UIM_dom.
DR InterPro; IPR002014; VHS_dom.
DR PANTHER; PTHR45929; JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE; 1.
DR PANTHER; PTHR45929:SF3; JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE; 1.
DR Pfam; PF00018; SH3_1; 1.
DR Pfam; PF02809; UIM; 1.
DR Pfam; PF00790; VHS; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 1.
DR SMART; SM00726; UIM; 1.
DR SMART; SM00288; VHS; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
DR PROSITE; PS50330; UIM; 1.
DR PROSITE; PS50179; VHS; 1.
PE 3: Inferred from homology;
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
SQ SEQUENCE 744 AA; 82648 MW; 06F17D3F9C1E858E CRC64;
MPLFTPTTPF DGDVEKATSE MNTEENWAVI MDIVDKVNTT NGSKDCLRSI AKRLNHRVPF
VAMQALTLLD ACVNNCGRPF HLEVSSRDFI SECRTLINQK AHPKVAQKLK SMIKKWAESK
EFKDEPTLSL IPSFYSSLKS EGIDFNDPDA PTKKTVQLSS NPDVANSQQE EDDLAKAIAL
SLKDSEKSSV KTTSLYPTGI NSSAIYATSS KPKEVRKVRA LYDFEAAEDN ELTFKSGEFI
SVTDDSDANW WKGFNHRGEG LFPANFVTSD LTVEPEESKA EKAVKFKEEV QVLDFESDDV
TIDEGKIDEA LQLIQNADPT GETQTDSTEM LRLENQCSRM GPLIDTELEK IDKKHASLCE
LNSKVVEAMQ MYHNLMKETP APYGYKGQQP PPSVSYSFPS QGAYNGQPQF QSGPSQLPPA
SRPQGPMPGG PMPLPQGAMP QNPGMVPQMP PNQMSINPQS YMPQGPSSQS YSKILVITTA
TGRATRLARD TPLPGVFSPA RRLTNGSLRT PVSNKRKLTV KLASAGTNDI GKAAQTQVKS
PPCNLYIGNN FCVRIYDFFD LQNSIQNNKR GGLVHIDFDP AVHFKAMTLS EGAEKIWSVP
NAGGNSVISE VLSFETFHRC FHAELLRTEM EVSYFPEGGS ITDYVCDIFG TKVGVSVTRA
MKYRGEYTEE DATNLLTKKL KGVNQANRNT LERWNKQILH VWVQNKEAAN LVTRAWQDLP
PDLVTNTMVV VSRTRRSDFI FYNP
//
