ID K1QK91_CRAGI Unreviewed; 817 AA.
AC K1QK91;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Prestin {ECO:0000313|EMBL:EKC29285.1};
GN ORFNames=CGI_10014593 {ECO:0000313|EMBL:EKC29285.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC29285.1};
RN [1] {ECO:0000313|EMBL:EKC29285.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC29285.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU362052}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362052}.
CC -!- SIMILARITY: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
CC {ECO:0000256|RuleBase:RU362052}.
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DR EMBL; JH815881; EKC29285.1; -; Genomic_DNA.
DR AlphaFoldDB; K1QK91; -.
DR HOGENOM; CLU_003182_9_4_1; -.
DR InParanoid; K1QK91; -.
DR OMA; AYGMCNF; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008509; F:monoatomic anion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0098661; P:inorganic anion transmembrane transport; IEA:UniProtKB-UniRule.
DR CDD; cd07042; STAS_SulP_like_sulfate_transporter; 1.
DR Gene3D; 3.30.750.24; STAS domain; 1.
DR InterPro; IPR011547; SLC26A/SulP_dom.
DR InterPro; IPR001902; SLC26A/SulP_fam.
DR InterPro; IPR002645; STAS_dom.
DR InterPro; IPR036513; STAS_dom_sf.
DR NCBIfam; TIGR00815; sulP; 1.
DR PANTHER; PTHR11814:SF257; ANION TRANSPORTER SULP-7D; 1.
DR PANTHER; PTHR11814; SULFATE TRANSPORTER; 1.
DR Pfam; PF01740; STAS; 1.
DR Pfam; PF00916; Sulfate_transp; 1.
DR SUPFAM; SSF52091; SpoIIaa-like; 1.
DR PROSITE; PS50801; STAS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362052};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362052};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362052}; Transport {ECO:0000256|RuleBase:RU362052}.
FT TRANSMEM 92..112
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 132..160
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 207..230
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 282..300
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 312..332
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 365..384
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 437..458
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 464..483
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 495..527
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
SQ SEQUENCE 817 AA; 90210 MW; 0A59797F48A6E9C8 CRC64;
MSMEDKSGVK DRRKSSPGGT TPVDSTIFIK RQPYTQAAFD EIYLKEKNTD KPPIYQRALE
KVSCTPKKVF KIFSSFLPII KAIRYYNLKE NAVTDILSGI TIGILHIPQA LAFGLLTSVK
VENGLYTSVW PIILYVIFGT SPHVSMGTSA VICIVTASVV DKQAEVFKAA NPTLIYSSLN
GSSNATLLEW ESIPAFMDYK EHVSMTISLF VGVILLIMGF LRLGFITAYL SESFFAAFTS
GAAVHIATSQ IPALLGISIP RYGGAFKIVK TYKAIFENIT DANVAAIVTT IICIAFIFLM
KECVNERFKD KLFIPIPVEL IVVIIATLAS YLGKLNEEFD LAIVGNIPST IPPPILPDTT
GVADYFVDCF VIAILIFANT IAMAKVCAKK HNYEVDDSQE LVAYGMCNFV SAFFRCFPSA
VAPPRSMVAS NMNAKSTLNG AFAALLMILV IMAMSVLFEP LPKAALSSII VAALKGLFIQ
MGDCRKYWRI NRIDFVIWFF TIVSVVFLDI DFGLGIGVIV SLITVVFQTQ FARGYRLGRI
TKDGAIVEYK RYSETIEDTG VKVFRFQANL FFANAEIFRN TLYKCTINPR KLLKFLKKQE
RKGGLKEKKV STDLTGVTVT GDRKASQVSI NSNGKDTFIN TASTANLTKS DNPVFSISDE
NLSRPPNYSG NGNYQGMPRQ MSTASSISQL GYEEDPETGD ELVTPEKIRI MRKTHHIIID
CSNINYLDAS GANVLGHISS EYNHVQVKVF LAGCSVDMIK TMTQASVFDR IPKENLFLTV
YDAIAVAKTQ SIRPLPPVVE DFDDEEAAED SYITNIQ
//
