ID K1QLN5_CRAGI Unreviewed; 772 AA.
AC K1QLN5;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Carnitine O-palmitoyltransferase 1, liver isoform {ECO:0000313|EMBL:EKC29705.1};
GN ORFNames=CGI_10006907 {ECO:0000313|EMBL:EKC29705.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC29705.1};
RN [1] {ECO:0000313|EMBL:EKC29705.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC29705.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
CC -!- SIMILARITY: Belongs to the carnitine/choline acetyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005232}.
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DR EMBL; JH816343; EKC29705.1; -; Genomic_DNA.
DR AlphaFoldDB; K1QLN5; -.
DR HOGENOM; CLU_013513_2_1_1; -.
DR InParanoid; K1QLN5; -.
DR OMA; ECDEIVH; -.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.30.559.70; Choline/Carnitine o-acyltransferase, domain 2; 1.
DR InterPro; IPR000542; Carn_acyl_trans.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR039551; Cho/carn_acyl_trans.
DR InterPro; IPR042231; Cho/carn_acyl_trans_2.
DR PANTHER; PTHR22589; CARNITINE O-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR22589:SF112; CHOLINE_CARNITINE ACYLTRANSFERASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00755; Carn_acyltransf; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EKC29705.1}.
FT DOMAIN 171..758
FT /note="Choline/carnitine acyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00755"
SQ SEQUENCE 772 AA; 89078 MW; E54653BDD04DFC6E CRC64;
MAEARCAVHE PSVPHASEEE YQRNIYNEWR RSLVRRFYRT RNLLYNGMWP TSIWNLAAMV
LILTVTMVTD TQLMKPVNER LWKVQHMLYI PKGLPLVVNA VITSCVVGFW FFLIKIYVRR
YLLRGLLSYR GWMYEQPKTQ SFSTLMWGIL VKLISGYSPK LYSCQSSLAR MPVPALRDTL
SKLLDSLEPL YGEDIGKWNK LKQDAADFER GYGPKLQRIL VLKSWWCNNY VTDWWEKYVY
LSSRGPLPIN SNYYILDQEH WTPSPIQTAR ISSTVYNLLK FKQLRDRETL KPLLIRNTIP
VCMAQYEKMF STTRIPGEEC DTLLTHNSTV SKHIAVFRKG VLYRCEMYDK NGRLLTPTLI
QKQLDWIIND ADKHADSYSR EEKTVASLTG QERAKWCKIR DRHFCEGVNR DTMDMIEKAM
FCLTLETEIY ETMSERGQYL LCKNDGKLWY DKCFNLVSFP DGRMGCNSEH SYADAPIIAH
LLEYNYTAEA LGQCGFQKDG SLTPDPEDSQ YILSLPTRHI WEITPDLRTA IVEAGKFCQM
NADDLDLCLR ELTVYGKGFM KSCKVSPDAF IQMALQLTYY KNAGKFALTY ESSMTRLYLQ
GRTETVRSLS NDSVAFVKAF LDKSVPKATT INLLRRACNR HQDAYRDAMS GQGIDRHLFA
LYVISKGMGY DCEFLKEALT IPWTLSTSQQ PQQQIATSPD CNLPQYRHAL CPGGGFGPVS
DDGYGVSYMI PGDHKVFFHV SSKRSTPGTD SVKFMDQLFE TFVELKELFS KD
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