ID K1QLW1_CRAGI Unreviewed; 478 AA.
AC K1QLW1;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Nuclear receptor ROR-beta {ECO:0000313|EMBL:EKC29815.1};
GN ORFNames=CGI_10007795 {ECO:0000313|EMBL:EKC29815.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC29815.1};
RN [1] {ECO:0000313|EMBL:EKC29815.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC29815.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004334}.
CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
CC {ECO:0000256|RuleBase:RU004334}.
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DR EMBL; JH817999; EKC29815.1; -; Genomic_DNA.
DR AlphaFoldDB; K1QLW1; -.
DR HOGENOM; CLU_496309_0_0_1; -.
DR InParanoid; K1QLW1; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd06916; NR_DBD_like; 1.
DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1.
DR Gene3D; 1.10.565.10; Retinoid X Receptor; 1.
DR InterPro; IPR035500; NHR-like_dom_sf.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR InterPro; IPR001723; Nuclear_hrmn_rcpt.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR45805; NUCLEAR HORMONE RECEPTOR HR3-RELATED; 1.
DR PANTHER; PTHR45805:SF2; NUCLEAR HORMONE RECEPTOR HR3-RELATED; 1.
DR Pfam; PF00104; Hormone_recep; 1.
DR Pfam; PF00105; zf-C4; 1.
DR PRINTS; PR00398; STRDHORMONER.
DR PRINTS; PR00047; STROIDFINGER.
DR SMART; SM00430; HOLI; 1.
DR SMART; SM00399; ZnF_C4; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1.
DR PROSITE; PS51843; NR_LBD; 1.
DR PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|RuleBase:RU004334};
KW Metal-binding {ECO:0000256|RuleBase:RU004334};
KW Nucleus {ECO:0000256|RuleBase:RU004334};
KW Receptor {ECO:0000256|RuleBase:RU004334, ECO:0000313|EMBL:EKC29815.1};
KW Transcription {ECO:0000256|RuleBase:RU004334};
KW Transcription regulation {ECO:0000256|RuleBase:RU004334};
KW Zinc {ECO:0000256|RuleBase:RU004334};
KW Zinc-finger {ECO:0000256|RuleBase:RU004334}.
SQ SEQUENCE 478 AA; 54848 MW; EAF9D2D769D5D44D CRC64;
MEPVSVQRKG KKREKYTCSH EPLEFPSCRV CGKKSTGIHF GVYSCEACKT FFRRSFLRST
PYKCDKGGDC LINAEKQNGS RPCPACRLVK CLDLGMSKDG VKQGRYTMTQ RTSVILEVQK
LRDQTSNRLA TDPENTHPGI QGDRQIKDGC ELDCNIFHQD SQDDGTLSET SGGSYTIHSS
SSSSNSPHIQ DKEIVELAQE VGRTSIILGE ESTKESGVPC LDKSEDILQR IMTGYGYLEH
FTKSMTDEEI QDILDKEWMK HTDKTKLFGK LEYLPTDQYN DIYEKTQLDV DGRKKLLSEA
KYEFMKMAND YVKFCKNIPF FSGLSSHFEF FTILQHKGMN TEKEMCISYT GKVLPLSETC
PYTSKETLLG WAEFSEEVSK LQLSPEEFAL MLGICVTFRD RCPLDYPEDV ENIQKRLLET
LEFTLSKSHY ENKGRRLAKL LDLFVRLRVI GDEYLELYKV ICQDPIMREN LPEFLIYL
//
