ID K1QPH4_CRAGI Unreviewed; 129 AA.
AC K1QPH4;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Caveolin {ECO:0000256|RuleBase:RU000680};
GN ORFNames=CGI_10007942 {ECO:0000313|EMBL:EKC30745.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC30745.1};
RN [1] {ECO:0000313|EMBL:EKC30745.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC30745.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
RN [2] {ECO:0000313|EnsemblMetazoa:G29517.1:cds}
RP IDENTIFICATION.
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EnsemblMetazoa:G29517.1:cds};
RG EnsemblMetazoa;
RL Submitted (AUG-2022) to UniProtKB.
CC -!- FUNCTION: May act as a scaffolding protein within caveolar membranes.
CC Interacts directly with G-protein alpha subunits and can functionally
CC regulate their activity. {ECO:0000256|RuleBase:RU000680}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004202,
CC ECO:0000256|RuleBase:RU000680}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004202, ECO:0000256|RuleBase:RU000680}. Golgi
CC apparatus membrane {ECO:0000256|RuleBase:RU000680}; Peripheral membrane
CC protein {ECO:0000256|RuleBase:RU000680}. Membrane, caveola
CC {ECO:0000256|RuleBase:RU000680}; Peripheral membrane protein
CC {ECO:0000256|RuleBase:RU000680}. Membrane
CC {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the caveolin family.
CC {ECO:0000256|ARBA:ARBA00010988, ECO:0000256|RuleBase:RU000680}.
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DR EMBL; JH816960; EKC30745.1; -; Genomic_DNA.
DR RefSeq; XP_011436020.1; XM_011437718.2.
DR EnsemblMetazoa; G29517.1; G29517.1:cds; G29517.
DR GeneID; 105334327; -.
DR KEGG; crg:105334327; -.
DR HOGENOM; CLU_102582_0_0_1; -.
DR OrthoDB; 2936017at2759; -.
DR Proteomes; UP000005408; Unplaced.
DR GO; GO:0005901; C:caveola; IEA:UniProtKB-SubCell.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0070836; P:caveola assembly; IEA:InterPro.
DR InterPro; IPR001612; Caveolin.
DR PANTHER; PTHR10844; CAVEOLIN; 1.
DR PANTHER; PTHR10844:SF19; CAVEOLIN-2; 1.
DR Pfam; PF01146; Caveolin; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|RuleBase:RU000680};
KW Golgi apparatus {ECO:0000256|RuleBase:RU000680};
KW Membrane {ECO:0000256|RuleBase:RU000680};
KW Reference proteome {ECO:0000313|Proteomes:UP000005408}.
SQ SEQUENCE 129 AA; 14529 MW; 4D75254E7BAF9F2C CRC64;
MSGDEIDLSN RDPNGLNAHL GTLHFNDVLG EPDGTHSIDM VWKCSHLCFN LWKGLCYKIL
TLCFGCCIAA EWGCEFAIIA FYHVWYITPC LKILEINCGL CQRIYTNCAN CCVVPCCEAF
GGLFHHFKK
//
