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Database: UniProt
Entry: K1QR55_CRAGI
LinkDB: K1QR55_CRAGI
Original site: K1QR55_CRAGI 
ID   K1QR55_CRAGI            Unreviewed;       602 AA.
AC   K1QR55;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   31-JUL-2019, entry version 27.
DE   SubName: Full=G protein-activated inward rectifier potassium channel 2 {ECO:0000313|EMBL:EKC39442.1};
GN   ORFNames=CGI_10020045 {ECO:0000313|EMBL:EKC39442.1};
OS   Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC   Eukaryota; Metazoa; Lophotrochozoa; Mollusca; Bivalvia; Pteriomorphia;
OC   Ostreoida; Ostreoidea; Ostreidae; Crassostrea.
OX   NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC39442.1, ECO:0000313|Proteomes:UP000005408};
RN   [1] {ECO:0000313|EMBL:EKC39442.1, ECO:0000313|Proteomes:UP000005408}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC39442.1,
RC   ECO:0000313|Proteomes:UP000005408};
RX   PubMed=22992520; DOI=10.1038/nature11413;
RA   Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA   Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W.H., Paps J.,
RA   Zhu Y., Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J.,
RA   Wen B., Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D.,
RA   Xu Z., Liu Y., Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B.,
RA   Cheng P., Jiang X., Li J., Fan D., Wang W., Fu W., Wang T., Wang B.,
RA   Zhang J., Peng Z., Li Y., Li N., Wang J., Chen M., He Y., Tan F.,
RA   Song X., Zheng Q., Huang R., Yang H., Du X., Chen L., Yang M.,
RA   Gaffney P.M., Wang S., Luo L., She Z., Ming Y., Huang W., Zhang S.,
RA   Huang B., Zhang Y., Qu T., Ni P., Miao G., Wang J., Wang Q.,
RA   Steinberg C.E.W., Wang H., Li N., Qian L., Zhang G., Li Y., Yang H.,
RA   Liu X., Wang J., Yin Y., Wang J.;
RT   "The oyster genome reveals stress adaptation and complexity of shell
RT   formation.";
RL   Nature 490:49-54(2012).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
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DR   EMBL; JH818808; EKC39442.1; -; Genomic_DNA.
DR   EnsemblMetazoa; EKC39442; EKC39442; CGI_10020045.
DR   InParanoid; K1QR55; -.
DR   Proteomes; UP000005408; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000005408};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609, ECO:0000313|EMBL:EKC39442.1};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005408};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM     74     97       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    150    174       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       39    179       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      186    357       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   REGION      456    523       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COILED      523    550       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   602 AA;  68618 MW;  93F14EFA6B65CAB0 CRC64;
     MFTEEKVEEK LSKLPFVNYV KQRFNLGQYN PEEQRRAIVQ KSGHYRVKYT GLKEYRAKFF
     QDLYITLIDL KWRYALAVLF NVHLLSYFFF ALMWYWMMYN HGDLDHLNDP KWESCVAGVH
     SFGDAMLFSI ESQTTIGYGF AYPNTDCGGA LPLLFVQITV GILLENVLLG FIFVKFAQPK
     RRRKTIMFSK VACVAQEEGD LCLQIRIGDM RQSHLIDAKV HGILIKRHVT REGVSYPLFQ
     HDVHFQANKM GDTIMLMWPL ILSHRITQES PFWDIRPSDL SSEAYELVVC IEGTLETTGE
     FCQARTSYLP SEILWGHRFD RIEEFDAGNG RWEIDFSGFN DVVYITNIRH SAKELNPYRE
     YRMSKEESEA TTKEKGLSIS LHSVAYDLPP EFPSASNSTE YQKSDIDGQS SQIRVNCFWA
     GDLRYIENNQ FWRNRCEIPP GVPGISILRE VIVKGEKGDR GPKGDMGPVG PKGEPGDTDD
     YGPPPRGPQG QRGQKGEPGA LGIRGPKGSL GAQGPKGDKG EPTEDIDEII LDLEARIQKL
     ESQLQDCSCE RPDPVNLTNF PPPPLPPVDS LRRKLMQELR EEGGECVSYA LRYYSQCSED
     GR
//
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