GenomeNet

Database: UniProt
Entry: K1QTN8_CRAGI
LinkDB: K1QTN8_CRAGI
Original site: K1QTN8_CRAGI 
ID   K1QTN8_CRAGI            Unreviewed;       404 AA.
AC   K1QTN8;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   08-MAY-2019, entry version 34.
DE   SubName: Full=Neuronal acetylcholine receptor subunit alpha-3 {ECO:0000313|EMBL:EKC37013.1};
GN   ORFNames=CGI_10025998 {ECO:0000313|EMBL:EKC37013.1};
OS   Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC   Eukaryota; Metazoa; Lophotrochozoa; Mollusca; Bivalvia; Pteriomorphia;
OC   Ostreoida; Ostreoidea; Ostreidae; Crassostrea.
OX   NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC37013.1, ECO:0000313|Proteomes:UP000005408};
RN   [1] {ECO:0000313|EMBL:EKC37013.1, ECO:0000313|Proteomes:UP000005408}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC37013.1,
RC   ECO:0000313|Proteomes:UP000005408};
RX   PubMed=22992520; DOI=10.1038/nature11413;
RA   Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA   Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W.H., Paps J.,
RA   Zhu Y., Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J.,
RA   Wen B., Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D.,
RA   Xu Z., Liu Y., Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B.,
RA   Cheng P., Jiang X., Li J., Fan D., Wang W., Fu W., Wang T., Wang B.,
RA   Zhang J., Peng Z., Li Y., Li N., Wang J., Chen M., He Y., Tan F.,
RA   Song X., Zheng Q., Huang R., Yang H., Du X., Chen L., Yang M.,
RA   Gaffney P.M., Wang S., Luo L., She Z., Ming Y., Huang W., Zhang S.,
RA   Huang B., Zhang Y., Qu T., Ni P., Miao G., Wang J., Wang Q.,
RA   Steinberg C.E.W., Wang H., Li N., Qian L., Zhang G., Li Y., Yang H.,
RA   Liu X., Wang J., Yin Y., Wang J.;
RT   "The oyster genome reveals stress adaptation and complexity of shell
RT   formation.";
RL   Nature 490:49-54(2012).
CC   -!- SIMILARITY: Belongs to the ligand-gated ion channel (TC 1.A.9)
CC       family. {ECO:0000256|RuleBase:RU000687,
CC       ECO:0000256|SAAS:SAAS00978283}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; JH818173; EKC37013.1; -; Genomic_DNA.
DR   RefSeq; XP_011452218.1; XM_011453916.2.
DR   RefSeq; XP_011452220.1; XM_011453918.2.
DR   EnsemblMetazoa; EKC37013; EKC37013; CGI_10025998.
DR   GeneID; 105345684; -.
DR   KEGG; crg:105345684; -.
DR   InParanoid; K1QTN8; -.
DR   OMA; NEEWDIV; -.
DR   OrthoDB; 845098at2759; -.
DR   Proteomes; UP000005408; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005230; F:extracellular ligand-gated ion channel activity; IEA:InterPro.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   Gene3D; 2.70.170.10; -; 1.
DR   InterPro; IPR006202; Neur_chan_lig-bd.
DR   InterPro; IPR036734; Neur_chan_lig-bd_sf.
DR   InterPro; IPR006201; Neur_channel.
DR   InterPro; IPR036719; Neuro-gated_channel_TM_sf.
DR   InterPro; IPR006029; Neurotrans-gated_channel_TM.
DR   InterPro; IPR018000; Neurotransmitter_ion_chnl_CS.
DR   PANTHER; PTHR18945; PTHR18945; 1.
DR   Pfam; PF02931; Neur_chan_LBD; 1.
DR   Pfam; PF02932; Neur_chan_memb; 1.
DR   PRINTS; PR00252; NRIONCHANNEL.
DR   SUPFAM; SSF63712; SSF63712; 1.
DR   SUPFAM; SSF90112; SSF90112; 1.
DR   PROSITE; PS00236; NEUROTR_ION_CHANNEL; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005408};
KW   Ion channel {ECO:0000256|RuleBase:RU000687};
KW   Ion transport {ECO:0000256|RuleBase:RU000687};
KW   Membrane {ECO:0000256|SAAS:SAAS00978300, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000313|EMBL:EKC37013.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005408};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00978734,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00978768,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU000687}.
FT   SIGNAL        1     20       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        21    404       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003851943.
FT   TRANSMEM    234    256       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    268    285       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    297    321       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    381    403       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       29    232       Neur_chan_LBD. {ECO:0000259|Pfam:
FT                                PF02931}.
FT   DOMAIN      239    344       Neur_chan_memb. {ECO:0000259|Pfam:
FT                                PF02932}.
SQ   SEQUENCE   404 AA;  46863 MW;  26B9D4714CB788A6 CRC64;
     MGRTFVYLCL CSRLLTIALC KTHDHPEYLL FDNLFNGYNP DVRPTLEYQH TLFMNVSVNL
     IALHSLEERS QTLTATVWID LEWTDVHLTW NGSEYNNIQS IIVPSEKIWN PDICVTNEVT
     NNKCLVRSED GKALLEHTGK VTIWWNKEVK TGCDVDISQY PFDTQNCAIK IGTWYSVDEN
     IRLVQKYDIL DLDNYSPNEE WDIVSSHVTE IPVEDELNYT DLQFSMVIDR RPLFYLYSTV
     LPILLLSVLN MVCFVVPVES GEKLGMTMAI FLTFAVFMTM ISSNIPRSSE HVFKFGIFMT
     MHLLMSGLTI MLEVFVTNIY YKPKDMKMNR FYEWVFRHLV DNDKNDNQIS ASRPANNRER
     FSCSVDETDS WQKLSLRLDK VFGYIVASIN TLLILLFFVT VSLG
//
DBGET integrated database retrieval system