ID K1QTP6_CRAGI Unreviewed; 1172 AA.
AC K1QTP6;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Putative cation-transporting ATPase 13A1 {ECO:0000313|EMBL:EKC37018.1};
GN ORFNames=CGI_10026003 {ECO:0000313|EMBL:EKC37018.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC37018.1};
RN [1] {ECO:0000313|EMBL:EKC37018.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC37018.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the cation transport ATPase (P-type) (TC 3.A.3)
CC family. Type V subfamily. {ECO:0000256|ARBA:ARBA00006000}.
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DR EMBL; JH818173; EKC37018.1; -; Genomic_DNA.
DR RefSeq; XP_011452247.1; XM_011453945.2.
DR AlphaFoldDB; K1QTP6; -.
DR GeneID; 105345690; -.
DR KEGG; crg:105345690; -.
DR HOGENOM; CLU_001828_4_1_1; -.
DR InParanoid; K1QTP6; -.
DR OMA; QKTKYVW; -.
DR OrthoDB; 6047at2759; -.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0140358; F:P-type transmembrane transporter activity; IEA:InterPro.
DR CDD; cd07543; P-type_ATPase_cation; 1.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR006544; P-type_TPase_V.
DR InterPro; IPR047820; P5A-type_ATPase.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01494; ATPase_P-type; 1.
DR NCBIfam; TIGR01657; P-ATPase-V; 1.
DR PANTHER; PTHR45630; CATION-TRANSPORTING ATPASE-RELATED; 1.
DR PANTHER; PTHR45630:SF7; ENDOPLASMIC RETICULUM TRANSMEMBRANE HELIX TRANSLOCASE; 1.
DR Pfam; PF13246; Cation_ATPase; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR PRINTS; PR00119; CATATPASE.
DR SFLD; SFLDG00002; C1.7:_P-type_atpase_like; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF81660; Metal cation-transporting ATPase, ATP-binding domain N; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
SQ SEQUENCE 1172 AA; 131008 MW; 670A0254F420E7D4 CRC64;
MAGPALSEDI QTISFHNLRP LYLHGTIGPF CILYLLWFYC WTVIYGVENY FEAGLIALVG
IALLQILAML FCVWSVDLRC WMTCSKVKHP DGAEWLKVTP MPNNGSTEFV KLHREKGDGK
HPDLWFVYQK TRYVYDREEK KQFVSAQFPV NLSVNEYMDW KGYQEEEELK QAEKKYGKNI
MEMDIPQFME LFKERATAPF FVFQVFCVGL WCLDEYWYYS IFTLFMLVAF EATLVQQQLR
NMAEIRKMGN KPYLIQVYRN RKWRPILSNE LIPGDLVSIG RSQEDRLVPC DLLLLRGPCI
VDESMLTGES VPVMKEALEN LDSHHVLDIE TDGKLHVLYG GTKVVQHTPP SKTGPGMKTA
DNGCVAYVLR HSFGTSQGKL LKTILFGVKR VTANNLETFG FILFLLVFAV TAASYVWIEG
TKDPKRNRYK LFLECTLILT SVVPPELPIE LSLAVNTSLL ALTKLYVYCT EPFRIPFAGK
VDICCFDKTG TLTADDLVVE GITGLNGKQM ITAAEAPLET VHVLATCHAL VHLEDDLVGD
PLEKATLKAV EWNLTKGESV VPQKKKTHGL KIYHRFHFAS ALKRMSVIAG HTAPGSLETE
YIATVKGAPE TLKPMFKEMP ADYDDVYMEM SRRGARVLAL GCKSLGSLSH QQVREMARDE
VEKDLQFCGF VIISCPLKSD SKAVIKEISQ ASHHVVMITG DNPLTACHVA KELKMTRKEM
LILEKPNALD GSWHWQSIDD KIILPLKPES LRTEVLPKYD LCLTGDAISY LQTQDKKCMK
SVLPAARVFA RVSPKQKEFV IITLKGLGFT TLMCGDGTND VGALKHAHVG VALLANAPER
PIERRRKREK QDEGTSVDGE ASGPSDRGMP PGMKTTGKLS GRAAKARAVA RGDNLAPAQK
KLANMMREIE EEEKAQIVKL GDASIASPFT SKLSTTMCVC HIIKQGRCTL VTTLQMFKIL
ALNALILAYS QSVLYLDGIK FSDSQATMQG LLLAGCFLFI SRSKPLKILS KARPLPNIFN
IYTLLTVSLQ FTVHFCCLVY LVQGAKAITP PREDEFVDLE AKFSPNILNT TVYIISMALQ
VSTFAVNYKG EPFMESLFNN KPLLYSLAFS CTAITALASG VVPDIADQFE IVPLPTEFRN
TVLQILAADI GGSFIIDRVC SYLFGRGSLR RV
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