ID   K1QTV7_CRAGI            Unreviewed;       792 AA.
AC   K1QTV7;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   13-SEP-2023, entry version 39.
DE   SubName: Full=Aldehyde dehydrogenase family 16 member A1 {ECO:0000313|EMBL:EKC34674.1};
DE   Flags: Fragment;
GN   ORFNames=CGI_10026809 {ECO:0000313|EMBL:EKC34674.1};
OS   Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC   Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX   NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC34674.1};
RN   [1] {ECO:0000313|EMBL:EKC34674.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC34674.1};
RX   PubMed=22992520; DOI=10.1038/nature11413;
RA   Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA   Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA   Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA   Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA   Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA   Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA   Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA   Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA   Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA   Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA   Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT   "The oyster genome reveals stress adaptation and complexity of shell
RT   formation.";
RL   Nature 490:49-54(2012).
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC       {ECO:0000256|RuleBase:RU003345}.
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DR   EMBL; JH817038; EKC34674.1; -; Genomic_DNA.
DR   AlphaFoldDB; K1QTV7; -.
DR   HOGENOM; CLU_018339_0_0_1; -.
DR   InParanoid; K1QTV7; -.
DR   OMA; MDYGPAP; -.
DR   GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   CDD; cd07111; ALDH_F16; 1.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR029510; Ald_DH_CS_GLU.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR011408; Aldehyde_DH.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR   PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF00171; Aldedh; 2.
DR   PIRSF; PIRSF036490; Aldedh_dupl; 1.
DR   SUPFAM; SSF53720; ALDH-like; 2.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|RuleBase:RU003345}.
FT   DOMAIN          18..461
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
FT   DOMAIN          530..756
FT                   /note="Aldehyde dehydrogenase"
FT                   /evidence="ECO:0000259|Pfam:PF00171"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:EKC34674.1"
SQ   SEQUENCE   792 AA;  87371 MW;  667511E8380AF8BB CRC64;
     AWLDDHGKDF GVFIDGKWVK PEGRKKYLTK NPATGEDLAW TTQAEKADVD LAVKAAEKAY
     QSWSKTSPHV RARHLYSIAR HIQKHMRLFN VVESLDNGKT IRETRDADIP TVVRHFYHHA
     GWAQLMETEM RGWKSVGVIG AIVPWNFPLM LLTWKIAPAL AMGNTVVLKP ATYTRLSALL
     LAEVCAEAGL PPGVFNVVTG SGAMGSMLAE HPSVDKVAFT GSTGVGQTLR RLTAGSGKKL
     SLELGGKSPV VVFESADLDS AVEGVVDAIW FNQGQVCSAG SKLLVQEPIY EKMVNKLKER
     LTHFRVGNSL DKTMDMGAIV DESQRKSIEE YVEEARKEGA EVFQIKDSVP SGCYYPPTII
     TNVQTVSRVV AEEIFGPVLV VLPFRTAKEA LAISNNTIYG LGGSVWTENV PLALEVALGI
     KAGTVWINCH NLFDAAAGFG GYKQSGYGRD GGKEGLFEYV RPAWEERPRP GKVQMDLKTF
     GATLPQRPTF ENVDNKQITI NGVTMPSIDR TFKMYYGGGQ KRPDAPYVRP VINPDGKVVG
     HVGEGNRKDV RNAVETAHAA APGWGKRAAH NRAQIVYYMA ENLEIRRDEI AGRIQLMTGR
     KLEECVTEVD LSIQRLFHWG AYCDKYGGGV QETTLYGATV KIHEPVGVIG MACPDAYPLL
     GFVSLFAPAV VRGNTMIIIP SQNYPLSALD LYQVFDTSDL PGGVVNILTG DRDHLTKYLT
     EHQDVQSMWY FGSAEGSKFV EFASAENVKR TWVNYGLERD WTDPEQGQGE EFLYQSVQVK
     NIWIPMGDIF AN
//