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Database: UniProt
Entry: K1QY50_CRAGI
LinkDB: K1QY50_CRAGI
Original site: K1QY50_CRAGI 
ID   K1QY50_CRAGI            Unreviewed;       683 AA.
AC   K1QY50;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   16-JAN-2019, entry version 26.
DE   SubName: Full=Low-density lipoprotein receptor-related protein 6 {ECO:0000313|EMBL:EKC26481.1};
GN   ORFNames=CGI_10007812 {ECO:0000313|EMBL:EKC26481.1};
OS   Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC   Eukaryota; Metazoa; Lophotrochozoa; Mollusca; Bivalvia; Pteriomorphia;
OC   Ostreoida; Ostreoidea; Ostreidae; Crassostrea.
OX   NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC26481.1, ECO:0000313|Proteomes:UP000005408};
RN   [1] {ECO:0000313|EMBL:EKC26481.1, ECO:0000313|Proteomes:UP000005408}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC26481.1,
RC   ECO:0000313|Proteomes:UP000005408};
RX   PubMed=22992520; DOI=10.1038/nature11413;
RA   Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA   Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W.H., Paps J.,
RA   Zhu Y., Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J.,
RA   Wen B., Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D.,
RA   Xu Z., Liu Y., Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B.,
RA   Cheng P., Jiang X., Li J., Fan D., Wang W., Fu W., Wang T., Wang B.,
RA   Zhang J., Peng Z., Li Y., Li N., Wang J., Chen M., He Y., Tan F.,
RA   Song X., Zheng Q., Huang R., Yang H., Du X., Chen L., Yang M.,
RA   Gaffney P.M., Wang S., Luo L., She Z., Ming Y., Huang W., Zhang S.,
RA   Huang B., Zhang Y., Qu T., Ni P., Miao G., Wang J., Wang Q.,
RA   Steinberg C.E.W., Wang H., Li N., Qian L., Zhang G., Li Y., Yang H.,
RA   Liu X., Wang J., Yin Y., Wang J.;
RT   "The oyster genome reveals stress adaptation and complexity of shell
RT   formation.";
RL   Nature 490:49-54(2012).
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00196}.
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DR   EMBL; JH816394; EKC26481.1; -; Genomic_DNA.
DR   PRIDE; K1QY50; -.
DR   EnsemblMetazoa; EKC26481; EKC26481; CGI_10007812.
DR   InParanoid; K1QY50; -.
DR   Proteomes; UP000005408; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR   Gene3D; 2.120.10.30; -; 2.
DR   Gene3D; 3.10.250.10; -; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR032485; DUF5050.
DR   InterPro; IPR000033; LDLR_classB_rpt.
DR   InterPro; IPR001190; SRCR.
DR   InterPro; IPR017448; SRCR-like_dom.
DR   InterPro; IPR036772; SRCR-like_dom_sf.
DR   Pfam; PF16472; DUF5050; 1.
DR   Pfam; PF00058; Ldl_recept_b; 2.
DR   Pfam; PF00530; SRCR; 1.
DR   PRINTS; PR00258; SPERACTRCPTR.
DR   SMART; SM00135; LY; 9.
DR   SMART; SM00202; SR; 1.
DR   SUPFAM; SSF56487; SSF56487; 1.
DR   PROSITE; PS51120; LDLRB; 9.
DR   PROSITE; PS00420; SRCR_1; 1.
DR   PROSITE; PS50287; SRCR_2; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005408};
KW   Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00196,
KW   ECO:0000256|SAAS:SAAS00873970};
KW   Lipoprotein {ECO:0000313|EMBL:EKC26481.1};
KW   Receptor {ECO:0000313|EMBL:EKC26481.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005408}.
FT   DOMAIN      135    238       SRCR. {ECO:0000259|PROSITE:PS50287}.
FT   REPEAT      245    288       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT      289    332       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT      333    375       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT      376    419       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT      425    467       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT      468    511       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT      512    554       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT      555    598       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   REPEAT      599    641       LDL-receptor class B.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00461}.
FT   DISULFID    207    217       {ECO:0000256|PROSITE-ProRule:PRU00196}.
SQ   SEQUENCE   683 AA;  74810 MW;  2F9448EE1462AA8F CRC64;
     MFFKLGPFIS GFLTPYCAAL ERDKKAVQSC YECSNIADPS QCTRVVTCRA NEVCYTEAHS
     TSSIFQSTVY SLGCRASTLC DAISHGGGVV GRKRNVRQLN THCNSCCRTN NCNRNLCGAT
     GHTGPTVSTS SSTYVRLLGG SHAYEGRVEV FHGGIWGSIC DDNWGGHEAQ VVCGMLGYSR
     SGSGGAQGGL FGAAPTYAKI FMDEVNCTGT EASIDLCHFN GWGVHDCGHD EDAGVICNSA
     STEDNIIFLL DTGLGGVIFR MDLNTQSYVP IPMNSLYTPT AFDYDPTDGR IYFVDYRLRQ
     LMSVHFSGTD VRELKQLDAN ADLEKIQVDP INRKLFYADT GNNLIGSINL DGTGYRVVVN
     QSLDEPRDLA LVPATQTIYW TDWGTSPKIE KASYDGSNRQ TLASTGLKWP NGLAYDYEDV
     TTIRDFVLVA DSYIQEIYRM DLETGSYSAI PQYSVNTPIG IDYDPLTHTV FYSDVGLHLI
     KSTDLDGNNE KILKRLNSVA IPDGLVIDVQ NRLIFYSDTG NDVIVKMNMD GTGVVNVTNT
     NLDEPRAVTL DVANQVIYWT DWGAHPKIEK SNYDGSNRQT LIDSGLKFPN GLVYDGTTNK
     LYLCDAGTNK IEVMDTNGQN RQLIFQDAGA HFFGIDVDSQ YIYVSDWTKD GVIRLNKDGS
     GETPVGPPSF GKLNGISLYH QGG
//
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