ID K1QZX2_CRAGI Unreviewed; 600 AA.
AC K1QZX2;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Xaa-Pro aminopeptidase 1 {ECO:0000313|EMBL:EKC26996.1};
GN ORFNames=CGI_10009528 {ECO:0000313|EMBL:EKC26996.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC26996.1};
RN [1] {ECO:0000313|EMBL:EKC26996.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC26996.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
CC -!- SIMILARITY: Belongs to the peptidase M24B family.
CC {ECO:0000256|ARBA:ARBA00008766}.
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DR EMBL; JH816771; EKC26996.1; -; Genomic_DNA.
DR AlphaFoldDB; K1QZX2; -.
DR HOGENOM; CLU_011781_2_2_1; -.
DR InParanoid; K1QZX2; -.
DR OMA; EPGMILS; -.
DR GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR CDD; cd01085; APP; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 2.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR InterPro; IPR033740; Pept_M24B.
DR InterPro; IPR032416; Peptidase_M24_C.
DR PANTHER; PTHR43763; XAA-PRO AMINOPEPTIDASE 1; 1.
DR PANTHER; PTHR43763:SF6; XAA-PRO AMINOPEPTIDASE 1; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF16189; Creatinase_N_2; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR Pfam; PF16188; Peptidase_M24_C; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
PE 3: Inferred from homology;
KW Aminopeptidase {ECO:0000313|EMBL:EKC26996.1};
KW Hydrolase {ECO:0000313|EMBL:EKC26996.1};
KW Protease {ECO:0000313|EMBL:EKC26996.1}.
FT DOMAIN 12..138
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 326..523
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
FT DOMAIN 535..599
FT /note="Peptidase M24 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16188"
SQ SEQUENCE 600 AA; 66727 MW; 47C35E15D8C0CE64 CRC64;
MPLAHNRTGP LLKKLRTLMS NRKYVPESIQ AYIVPSGDAH QSEYIAPCDC RRAFISGFNG
SAGTAVITTD KAALWTDGRY FLQAEKQLDE NWILMKDGQP NTPTQADWLA KELPVGGKVG
VDPCLISAEA WSPLKKNLLS SGHSIIAVPI NLIDLVWEDQ PPPPLNPLLT LTEKYTGISW
QDKIQKIREK MQTKKCGALV ISALDEIAYL FNLRGSDIEY NPVFFAYAVV TLDNIFLFID
DQKLDAEVKH HLQLNGTDSA IQVTSYDKVG EVIKNLVDQV EGKFWISPKC SVALTQCVEK
TRLFAQTSPV AVMKAVKNDT EIQGMRSAHI KDAVTLCELF SWLEKQIPTG EQEDFISLSF
ATISSTGPNA AIIHYKPTEE SDTVLSTDEI YLCDSGGQYK DGTTDVTRTI HFGSPSNHEK
ECYTRVLKGH IALASIIFPN ETKGHMLDTL ARTSLWEVGL DYAHGTGHGV GAFLNVHEGP
CGISPRVSAA EIPLEAGMIL SDEPGYYEDG KFGVRIENLV LVVKAETKFN FRNKGFLTFE
PITLVPMQLK MVVPSLLTEK EISWLNEYHT QCREVVGPEL KRQGKKEAYE WLMKETQSIG
//
