ID   K1R3G4_CRAGI            Unreviewed;      1669 AA.
AC   K1R3G4;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   RecName: Full=NACHT domain-containing protein {ECO:0000259|Pfam:PF05729};
GN   ORFNames=CGI_10018353 {ECO:0000313|EMBL:EKC35700.1};
OS   Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC   Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX   NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC35700.1};
RN   [1] {ECO:0000313|EMBL:EKC35700.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC35700.1};
RX   PubMed=22992520; DOI=10.1038/nature11413;
RA   Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA   Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA   Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA   Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA   Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA   Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA   Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA   Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA   Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA   Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA   Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT   "The oyster genome reveals stress adaptation and complexity of shell
RT   formation.";
RL   Nature 490:49-54(2012).
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DR   EMBL; JH817458; EKC35700.1; -; Genomic_DNA.
DR   HOGENOM; CLU_001985_0_0_1; -.
DR   InParanoid; K1R3G4; -.
DR   OMA; YSEMANY; -.
DR   Gene3D; 1.25.40.370; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR19871; BETA TRANSDUCIN-RELATED PROTEIN; 1.
DR   PANTHER; PTHR19871:SF14; DUF4062 DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF05729; NACHT; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR   SUPFAM; SSF50960; TolB, C-terminal domain; 1.
PE   4: Predicted;
FT   DOMAIN          325..489
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|Pfam:PF05729"
SQ   SEQUENCE   1669 AA;  189222 MW;  6C22B1CA7301A03F CRC64;
     MDEATKKLLS GHVRIEDIDE IPARTVRVFL NSAGVDSVTE RNSIVEKVYP QLRDHCRQKH
     GVEFQLVDLD WGADPNGVNL DQSFYDFRLR ELRRCQILTA GPSFLKEKSV FNEGLAKWRE
     TEGEIMRLLH KAAEACYLQG IIDEGIKQKY VLSAIDNLMI LGIDEIASPE NQCLIAFREI
     ADLRNYVNDP LAEKFADIFF NERTDQNEID PVSTHLIKTM SDRSRKLVSD KNTTFYSVLW
     RYDDVISPIH HKEYLSKLCS DLSSALKQLI DKDVPKTIFD EKDEVFDECH QHWLRCKHLS
     ADFHGRESEY AKVVEYIQGS TETPLVIHGA TGEGKTALLS KVASQVHDLI PTNRICIMKY
     VGYTPKSSDV RTLLTSICTQ ILVGLGRDHM SISRDFKELQ KFFLSLLQSI PQNKKLLIFL
     DAVEQILPDH NAHLLTWLPQ TLMSNVKIIL SVNSGDSTIA QKLCNGADKN SRSFVELKPL
     SVSEADDLLC YCLNRYGRTL SNQQRSALTN VFQKCSQPLF VSLCAEKCKC IHSNDSIDTA
     DFSTSLGDSI SAMLTDLEKK HGYELVSRSM SYLVGSVTGL SDSEMEDLLS LDDHVMSVIY
     SNHKPSLWRI PHNKWLRLKD EIDRYFVQRE VDGVTVYRWK DEQFNQIIRE KYLNDESKTK
     EIYSLIADYY LGIWHGKPKP LSTAEDNGKS PAFDRHVPSQ PLTFDNDGQV RFNRRKYDQV
     PRHLYNAERL DELNRLVLFN YEWIYNKIKA LSLQHIIADF ALNPSNEASL VEEALRVAEQ
     VIEKDIDNMA SEISGHLLPY YQTHPNIRAL VHQCDTAGLK QCALIPNFPY LQIPGSSLQF
     ALKCGAPMEY FSLIGDERFL LTKERESSFV HIFDVVLGEK KSSVFASNGA LYVTPNGRYF
     IIIDHVTEKS VKIHNAETGA YVGQLIVLNH IDLKPKEKYK LGSICLTNDR ICAIVSTDVS
     YLCIASIESC QFLQIIGLDG KCDVCTISHD GKYVFCNSNE FLFTYNLYTL ELVATFSIGF
     RPSCIVVSKD CMRAYLTNNF ETKLMILHLN QGKVEMAYKS VLDKYMADDT IMDLRISPKD
     DMVLVRGLNN ILVYNRANER VIASFTRPVD IPKEFKLPRS HYTDLVFTNA EFTHSGKFVI
     ATIFRNIYLW EVTTNELVTT IQAPVGIIKE MIYSPKRSHL ITHIEHCHEF QVWNLDEAVK
     PMNMLDKLTG AIADIQLTQD GETAYVTCKC SDEIGVIEMK TGIMVDLLTH DSPVVDFAIT
     PSGGFALVSL EPRKKDISTK LWNLKERQVI KEFGNASGYC ISPHQNDFIL FVSQQEVAFK
     APFFITMFQI SDEEVSEFTH PLALRFVLEK PFLTSNDKYL VVLTAHEYHE SRAEYETPTI
     CTFSMGEEMK VSYFTPDSFR DSILIETIVD MQPCLDNPYT IAVMYKSKEM VDYNDNSPFG
     GLGGGARYGF MILDICSGSV VTICDPFLVP SFQLKRKLLF DISYSFCLDD ESNIFDIREG
     CYVGQLPKQN SPPRAIALNG TVVVYYDRSV LSAYRLSSGE PIASCDVHSN ICSLRLSRDQ
     RTLVVGCEDG SIASYVLIDP KAENPNSVLE HLGSRQLMEP QPTSGRRSSI PWDKIEDGGS
     APQSRPVSAV AHDKTDKILL KQIEPVPAIR PSSDTLMYLN ANSKTCALM
//