ID K1R7W4_CRAGI Unreviewed; 691 AA.
AC K1R7W4;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Protocadherin Fat 4 {ECO:0000313|EMBL:EKC39719.1};
GN ORFNames=CGI_10018136 {ECO:0000313|EMBL:EKC39719.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC39719.1};
RN [1] {ECO:0000313|EMBL:EKC39719.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC39719.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
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DR EMBL; JH818281; EKC39719.1; -; Genomic_DNA.
DR AlphaFoldDB; K1R7W4; -.
DR HOGENOM; CLU_398647_0_0_1; -.
DR InParanoid; K1R7W4; -.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 4.
DR Gene3D; 2.60.40.60; Cadherins; 7.
DR InterPro; IPR039808; Cadherin.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR PANTHER; PTHR24027; CADHERIN-23; 1.
DR PANTHER; PTHR24027:SF445; CADHERIN-87A; 1.
DR Pfam; PF00028; Cadherin; 4.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 6.
DR SUPFAM; SSF49313; Cadherin-like; 6.
DR PROSITE; PS00232; CADHERIN_1; 4.
DR PROSITE; PS50268; CADHERIN_2; 6.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 35..141
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 166..244
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 245..353
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 363..490
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 491..598
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 599..685
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
SQ SEQUENCE 691 AA; 77430 MW; D76D80B752D96FFC CRC64;
MHGYVVHIRH QGIWETWLRF DITIEDINDN APVFTQSNYS LSINEETTKP NITTVQAKDS
DSGENATIKY KLIPSKWSSY FHIDPNSGKI NLNKTIDRET MGSLGILELT VVAEDGGKPS
RNSTALITIK INDINDNVPE FCNDGQTLEF TFNELDTKKD FYTAKATDKD ADDHDGILFA
LVNETSSFSI TKGVLSIKSR LKKTDAGVLM IVTYNNRPYA KELSNKTQKI SIKVQDINDN
IPNFNQTGYQ ISVKENTAVG SMLLSVTATD ADWSEEYGSV YYWISSGNTD RHFFINQLNG
SVYLADNVDY EKRTNYNLTI TASDYKDRKF SNHSAYTTLN ITVQDVNDES PKFADNCLQI
CKVKENTTGS FNCKVNATDH DRSKQFHHVT YQMVPSSGSS QTKRAIVNVT VLDVNDNRPN
FGGTLLTYNT SEGSTSKNLK ISFTATDLDI GNNGNVTYTM RDDYDSLFKM NSTDPINIYV
SDVNDCSPEF EKLNMTATIM EGSVKGFSVY RVTATDCDYD PQNRNLTYSI NGTDKEYFSI
KKEVHGDMQD GIVKLTKPIS VINKEIYKVN VTVSDGKNSN QTLLTVTVKD VNDHDPIFTQ
KKYNFNVSEN DSDGNRSMNA FVGKVNANDK DKHSSIVYRI VTSDVENLFN VTQDGVIHLI
GVVDHDSCSS HQFSFSVVAE DGGSPKRMVR R
//
