ID K1RAK5_CRAGI Unreviewed; 604 AA.
AC K1RAK5;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Aquaporin-8 {ECO:0000313|EMBL:EKC40659.1};
GN ORFNames=CGI_10018627 {ECO:0000313|EMBL:EKC40659.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC40659.1};
RN [1] {ECO:0000313|EMBL:EKC40659.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC40659.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MIP/aquaporin (TC 1.A.8) family.
CC {ECO:0000256|ARBA:ARBA00006175}.
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DR EMBL; JH816998; EKC40659.1; -; Genomic_DNA.
DR AlphaFoldDB; K1RAK5; -.
DR HOGENOM; CLU_452169_0_0_1; -.
DR InParanoid; K1RAK5; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015267; F:channel activity; IEA:InterPro.
DR Gene3D; 1.20.1080.10; Glycerol uptake facilitator protein; 3.
DR InterPro; IPR023271; Aquaporin-like.
DR InterPro; IPR034294; Aquaporin_transptr.
DR InterPro; IPR000425; MIP.
DR InterPro; IPR022357; MIP_CS.
DR PANTHER; PTHR19139:SF199; AQUAPORIN; 1.
DR PANTHER; PTHR19139; AQUAPORIN TRANSPORTER; 1.
DR Pfam; PF00230; MIP; 3.
DR PRINTS; PR00783; MINTRINSICP.
DR SUPFAM; SSF81338; Aquaporin-like; 3.
DR PROSITE; PS00221; MIP; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
SQ SEQUENCE 604 AA; 66745 MW; C1185BABC2AC5F7C CRC64;
MSQSEILTPT YEIGNTSFYE SHVRPVVVEF LGTTILVFLV CMFPATSSTI YQSAFVYGFA
TLFLIVSFGD TSGGHFNPAI TLGCTVAGAL SIPLSVCYFF AQILGGMLGA AFVRAVYPLK
IYKTIVGGST VLNSMQGMKP GWGVMTEALL TFIIVLTFLH SVVDKRRISK WKNTVCYFFA
QILGGMLGAA FVRAVYPLKI YKTIVGGSTV LNSMQGMKPG WGVMTEALLT FIIVLTFLHS
VVDKRSKLAP LSVGVSVAAC SFVGAFPTGG SMNPARSLGP AIAFSVYSDY VDDLIWKYHY
IYWVGPLAGT LFAALMYRIN EHPPPSRIRS LRFVENPGTH VCFPQKLFFK HSPASFLDEL
AKSNKIEGLL HLKPAHSQQS VMRKRSKRSG RLCRSVCGKS FSQKYLGRKM SESNDFIIEE
EKITDTSIFE SRVRPILAEF MGSIILVSVV CVGAVNTEST TMNAVIYGFT MMFLIITFGE
MSGGYFNPVI TLGYTLARVL SIPQAVCYFF AQIIGGIVGA ALVRASSPNR KYIPEFNGYH
SLWFYRMDEM ETQMTIMLSE AIPTFILVLT VLITTLDRKK RWLSPLAIGF SIIVCSYTGY
LDQF
//
