ID   K1RBJ4_CRAGI            Unreviewed;       913 AA.
AC   K1RBJ4;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   SubName: Full=Sodium bicarbonate transporter-like protein 11 {ECO:0000313|EMBL:EKC38585.1};
GN   ORFNames=CGI_10025939 {ECO:0000313|EMBL:EKC38585.1};
OS   Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC   Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX   NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC38585.1};
RN   [1] {ECO:0000313|EMBL:EKC38585.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC38585.1};
RX   PubMed=22992520; DOI=10.1038/nature11413;
RA   Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA   Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA   Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA   Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA   Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA   Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA   Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA   Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA   Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA   Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA   Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT   "The oyster genome reveals stress adaptation and complexity of shell
RT   formation.";
RL   Nature 490:49-54(2012).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the anion exchanger (TC 2.A.31) family.
CC       {ECO:0000256|ARBA:ARBA00010993}.
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DR   EMBL; JH817665; EKC38585.1; -; Genomic_DNA.
DR   AlphaFoldDB; K1RBJ4; -.
DR   HOGENOM; CLU_002289_6_0_1; -.
DR   InParanoid; K1RBJ4; -.
DR   OMA; PDSKHQD; -.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005452; F:solute:inorganic anion antiporter activity; IEA:InterPro.
DR   GO; GO:0006820; P:monoatomic anion transport; IEA:InterPro.
DR   Gene3D; 1.10.287.570; Helical hairpin bin; 1.
DR   InterPro; IPR011531; HCO3_transpt-like_TM_dom.
DR   InterPro; IPR003020; HCO3_transpt_euk.
DR   InterPro; IPR016152; PTrfase/Anion_transptr.
DR   InterPro; IPR002178; PTS_EIIA_type-2_dom.
DR   PANTHER; PTHR11453; ANION EXCHANGE PROTEIN; 1.
DR   PANTHER; PTHR11453:SF82; SOLUTE CARRIER FAMILY 4 MEMBER 11; 1.
DR   Pfam; PF00955; HCO3_cotransp; 1.
DR   PRINTS; PR01231; HCO3TRNSPORT.
DR   SUPFAM; SSF55804; Phoshotransferase/anion transport protein; 1.
DR   PROSITE; PS51094; PTS_EIIA_TYPE_2; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
SQ   SEQUENCE   913 AA;  102356 MW;  44BD6AE9D8B52699 CRC64;
     MPLQRVKMKM RPKKRVRFAI DLDDMSDAET SGDDPTWHSG NHEEEAVGPE DVQLLEVPNG
     SHGGPSGNSS SLLTSSESSS PSTPPVTWRD VCELISLFSL YTAGSFPTPY RDYSSFILSL
     TDEDDFALLH GRFEKVPLKD FHAEIRAFKD VEDFLSRTLL MLDLQKTGLT QIIEAMVQKL
     LEKKEVSAQT SLEEARHAIF TQDSVHTLSK TIQGTMTSEV SGFDFDQNWI CVMCDIPTVT
     KRHVVIARLH SPANLGSNSH EVQFVILVMA PVREKSTKSS LETARTFATL FLDIDFRHQL
     LLAESEYEFK QLLHTRTKLL IEEQGLPENR KSHLVLSAFE QEEQEGGKAR CPLGQGLIRD
     LKRRLPHYVS DFRDGFVGNK TIHKVTSTTF FLYFACVLPN IAFGMLNDNN TAGVIDVQKV
     LFSQCVGGLL FAVFGGQPLI VLLTTAPLAL YTKIIYSICE DFDLNFNAMF ACTGLWNAFF
     LLIFVFFNTS KLMKYSSRST EEVFSLFITF AFSADAIKDT IKDFNKNYNT DVCHGVTHSN
     STNQNASFPT NSSLTTVSAM TTASTVTTVS MVNVTNSSML AAPSGGGGIE ECLRENSILF
     LLLMLGTVWL GITLFNFTKT PFLNAGKREM LADYALPVAV LVMSFFGSYV FREVHMKPFK
     YKAREQMFEL APLHLLPVGA VFAAAGLGFS LSLLFFMDQN ISSALVNAPS NKLKKGAAYH
     WDLFVVAVIN AFLSIFTMPW VHAALPHSPL HVRALADLED RVDQGHVHQI VVHVRETRVT
     GIISHVMIGL SMLMLPYPLA YIPRPVLDGL FIYVAITALY GNQLFDRILL FFTEQSAYPP
     NHYIRRVPQR KIHLFTTLQL IQLVVLCVFG FSPIPYMKMV FPVLIMLLMP IRHKIIPNFF
     EPKYLKALDG HAH
//