ID K1S045_CRAGI Unreviewed; 538 AA.
AC K1S045;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE RecName: Full=TIR domain-containing protein {ECO:0000259|Pfam:PF13676};
GN ORFNames=CGI_10021876 {ECO:0000313|EMBL:EKC40631.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC40631.1};
RN [1] {ECO:0000313|EMBL:EKC40631.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC40631.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
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DR EMBL; JH817080; EKC40631.1; -; Genomic_DNA.
DR AlphaFoldDB; K1S045; -.
DR HOGENOM; CLU_040588_0_0_1; -.
DR InParanoid; K1S045; -.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR46270; ARMADILLO-TYPE FOLD-RELATED; 1.
DR PANTHER; PTHR46270:SF2; TIR DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13676; TIR_2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
PE 4: Predicted;
FT DOMAIN 334..441
FT /note="TIR"
FT /evidence="ECO:0000259|Pfam:PF13676"
SQ SEQUENCE 538 AA; 61122 MW; EE0EBBFFB67FCEE1 CRC64;
MEKKKKIKER ITEDITTSLS AIREGRSQGK SLDSPEVCES IRKLTKKIAS IMRTELKFSE
KFELGDQMCA KVLKEGTLVD DMMDFCLQHK DKLPVIAPGV DVIWRFFMNG TMFSPDLSRK
ISGKVGFLSY GKDVLESLYD LYVNKKTIRN QVHTLDSIST TTHNMCTFCD VTISDVRAAG
FLAVYLKYLK HEAVKDEFVK GVPILTAASD IMNENDASIT GNRRDVEYMI RGIKEAIQSP
SGQSRCWFAF ELGKTATKAL AHLAFDDDNK KTFVSDTQTD VVTTLFDLAR SSRYPDVRES
AKGVLWTLSE QLHSSTKYAD LVQKLFGKKT KGHVMISYSQ EQRPLLLRIK QAITEAGFSV
WMDIEQMREN VYDRMAEAIQ DASVVLISMS YSYQRSEYCR REAAYASSLK RARIPLLVDP
GYTAEGWLAL MTAGDYHYDF GREPFETKIV ELIEELERRC LKGQGEVTDG VVKQKVVSAS
KKSPSLLELQ EDLLRTEKRK LELGMEVLAV KKGKLEEEIG VLKLQKEKLR EEISIIRK
//
